Transcriptomic and proteomic of gastrocnemius muscle in peripheral artery disease
Background: Few effective therapies exist to improve lower extremity muscle pathology and
mobility loss due to peripheral artery disease (PAD), in part because mechanisms …
mobility loss due to peripheral artery disease (PAD), in part because mechanisms …
[HTML][HTML] Unveiling the Genetic Footprint: Exploring Somatic Mutations in Peripheral Arterial Disease Progression
AA Salybekov, M Hassanpour - Biomedicines, 2023 - mdpi.com
Peripheral arterial diseases (PADs) are complex cardiovascular conditions influenced by
environmental factors and somatic mutations in multiple genes involved in hematopoiesis …
environmental factors and somatic mutations in multiple genes involved in hematopoiesis …
Single-nuclei RNA-sequencing of the gastrocnemius muscle in peripheral artery disease
BACKGROUND: Lower extremity peripheral artery disease (PAD) is a growing epidemic
with limited effective treatment options. Here, we provide a single-nuclei atlas of PAD limb …
with limited effective treatment options. Here, we provide a single-nuclei atlas of PAD limb …
Single-cell meta-analysis of neutrophil activation in Kawasaki disease and multisystem inflammatory syndrome in children reveals potential shared immunological …
BACKGROUND: Kawasaki disease (KD) and multisystem inflammatory syndrome in
children (MIS-C) share similar clinical manifestations, including cardiovascular …
children (MIS-C) share similar clinical manifestations, including cardiovascular …
Multiomics analyses of peripheral artery disease muscle biopsies
Peripheral artery disease (PAD) affects 10 mil-lion people in the United States and> 230
million worldwide. 1, 2 It is associated with impaired vascular perfusion to the lower …
million worldwide. 1, 2 It is associated with impaired vascular perfusion to the lower …
An inflammatory transcriptomic signature in psoriasis associates with future cardiovascular events
Background Psoriasis is an inflammatory skin disease associated with increased
cardiovascular (CV) risk, whose pathogenesis is not fully known. Objective We identified a …
cardiovascular (CV) risk, whose pathogenesis is not fully known. Objective We identified a …
AhR regulates VEGF expression by promoting STAT1 transcriptional activity, thereby affecting endothelial angiogenesis in acute limb ischemia
J Ma, J Chen, H Wang, D Lu, K Liang - Chemico-Biological Interactions, 2023 - Elsevier
Background Angiogenesis has great potential in the treatment of acute limb ischemia (ALI).
Here, we aimed to investigate the effect and mechanism of Aryl hydrocarbon receptor (AhR) …
Here, we aimed to investigate the effect and mechanism of Aryl hydrocarbon receptor (AhR) …
Multi-Omic Analysis of Blood-Based Biospecimens for Molecular Signature Discovery
MIG Cornwell - 2023 - search.proquest.com
The use of sequencing technology in liquid-biopsy can help bridge the bench-to-bedside
gap by enabling a precision medicine focused approach to aid in the diagnosis and …
gap by enabling a precision medicine focused approach to aid in the diagnosis and …