The role of Lonp1 on mitochondrial functions during cardiovascular and muscular diseases
G Zanini, V Selleri, M Malerba, K Solodka, G Sinigaglia… - Antioxidants, 2023 - mdpi.com
The mitochondrial protease Lonp1 is a multifunctional enzyme that regulates crucial
mitochondrial functions, including the degradation of oxidized proteins, folding of imported …
mitochondrial functions, including the degradation of oxidized proteins, folding of imported …
Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca2+-dependent FUNDC1 phosphorylation at the ER-mitochondria interface
A Ponneri Babuharisankar, CL Kuo, HY Chou… - Cell death & …, 2023 - nature.com
During hypoxia, FUNDC1 acts as a mitophagy receptor and accumulates at the ER
(endoplasmic reticulum)-mitochondria contact sites (EMC), also called mitochondria …
(endoplasmic reticulum)-mitochondria contact sites (EMC), also called mitochondria …
Molecular determinants of mitochondrial shape and function and their role in glaucoma
O Khalimonchuk, DF Becker - Antioxidants & Redox Signaling, 2023 - liebertpub.com
Significance: Cells depend on well-functioning mitochondria for essential processes such as
energy production, redox signaling, coordination of metabolic pathways, and cofactor …
energy production, redox signaling, coordination of metabolic pathways, and cofactor …
Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions
D Li, TW Wang, S Aratani, S Omori… - The Journal of …, 2023 - academic.oup.com
The LONRF family of proteins consists of three isozymes, LONRF1–3, which harbors RING
(really interesting new gene) domain and Lon substrate binding domain. We have recently …
(really interesting new gene) domain and Lon substrate binding domain. We have recently …
[HTML][HTML] Pharmacological progress of mitophagy regulation
With the advancement in novel drug discovery, biologically active compounds are
considered pharmacological tools to understand complex biological mechanisms and the …
considered pharmacological tools to understand complex biological mechanisms and the …
The first case report of CODAS syndrome in Chinese population caused by two LONP1 pathogenic mutations
Y Tang, YX Liu, Y Sheng, LL Fan, AQ Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: CODAS syndrome (MIM 600373) is a multi-system developmental disorder
characterized by cerebral, ocular, dental, auricular, and skeletal anomalies. CODAS …
characterized by cerebral, ocular, dental, auricular, and skeletal anomalies. CODAS …
Danlu Tongdu tablets treat lumbar spinal stenosis through reducing reactive oxygen species and apoptosis by regulating CDK2/CDK4/CDKN1A expression
X Bai, AT Tahir, Z Yu, W Cheng, B Zhang… - arXiv preprint arXiv …, 2023 - arxiv.org
Lumbar spinal stenosis (LSS) is caused by the compression of the nerve root or cauda
equina nerve by stenosis of the lumbar spinal canal or intervertebral foramen, and is …
equina nerve by stenosis of the lumbar spinal canal or intervertebral foramen, and is …
Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca2+-dependent FUNDC1 phosphorylation at the ER-mitochondria interface.
CL Kuo, HY Chou, V Tangeda, CC Fan… - Cell Death & …, 2023 - europepmc.org
During hypoxia, FUNDC1 acts as a mitophagy receptor and accumulates at the ER
(endoplasmic reticulum)-mitochondria contact sites (EMC), also called mitochondria …
(endoplasmic reticulum)-mitochondria contact sites (EMC), also called mitochondria …
[PDF][PDF] Mitochondrial Lon-induced mitophagy benefits hypoxic resistance via Ca 2-dependent FUNDC1 phosphorylation at the ER-mitochondria interface
AP Babuharisankar, CL Kuo, HY Chou, V Tangeda… - 2023 - researchgate.net
Autophagy, a critical degradation mechanism of various intracellular components through
the formation of double-bilayered membrane vesicles called autophagosomes and its fusion …
the formation of double-bilayered membrane vesicles called autophagosomes and its fusion …
[图书][B] Revealing functional details of the mitochondrial Lon Protease by NMR spectroscopy
Y Sallova - 2023 - gupea.ub.gu.se
The hexameric Lon protein is an ATP-dependent protease residing in the mitochondrial
matrix. The Lon protein is the product of the nuclear LONP1 gene and plays a crucial role in …
matrix. The Lon protein is the product of the nuclear LONP1 gene and plays a crucial role in …