Cefiderocol, a siderophore cephalosporin, as a treatment option for infections caused by carbapenem-resistant Enterobacterales

KS Kaye, T Naas, JM Pogue, GM Rossolini - Infectious Diseases and …, 2023 - Springer
Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …

[HTML][HTML] Epidemiology, risk factors, and clinical outcomes of carbapenem resistant Enterobacterales in Africa: A systematic review

M Kedišaletše, D Phumuzile, D Angela… - Journal of Global …, 2023 - Elsevier
Abstract Background Carbapenem-resistant Enterobacterales (CRE) commonly cause
hospital-acquired infections and hospital outbreaks worldwide, with an alarming increase in …

Phenotypic and molecular characterization of beta-lactam resistant Multidrug-resistant Enterobacterales isolated from patients attending six hospitals in Northern …

N Medugu, IA Tickler, C Duru, R Egah, AO James… - Scientific reports, 2023 - nature.com
Infections caused by multi-drug resistant Enterobacterales (MDR-E) are difficult to treat and
cause significant mortality, especially in developing countries. This study characterized the …

Risk factors and clinical outcomes of carbapenem-resistant Klebsiella pneumoniae bacteraemia in children: a retrospective study

H Meng, J Yang, M Niu, H Zhu, Y Zhou, J Lu - International journal of …, 2023 - Elsevier
ABSTRACT Objectives Carbapenem-resistant Klebsiella pneumoniae (CRKP) is
increasingly being identified in children, but data on the clinical outcomes in this population …

The shared NDM-positive strains in the hospital and connecting aquatic environments

H Zou, J Han, L Zhao, D Wang, Y Guan, T Wu… - Science of The Total …, 2023 - Elsevier
The spread of antibiotic-resistant priority pathogens outside hospital settings is, both, a
significant public health concern and an environmental problem. In recent years, New Delhi …

Characterization of NDM-5-Producing Escherichia coli Strains Isolated from Pediatric Patients with Bloodstream Infections in a Chinese Hospital

L Huang, H Hu, C Xu, M Zhou, Y Li, Y Li, S Wu, N Dong - Genes, 2023 - mdpi.com
Escherichia coli (E. coli) bloodstream infections (BSIs) are among the most predominant
causes of death in infants and children worldwide. NDM-5 (New Delhi Metallo-lactamase-5) …

Directed carbapenemase testing is no longer just for Enterobacterales: cost, labor, and workflow assessment of expanding carbapenemase testing to carbapenem …

CM Gill, P Rajkotia, AL Roberts… - Emerging Microbes & …, 2023 - Taylor & Francis
Molecular carbapenem-resistance testing, such as for the presence of carbapenemases
genes, is commonly implemented for the detection of carbapenemase-producing …

Cefepime in vivo activity against carbapenem-resistant Enterobacterales that test as cefepime susceptible or susceptible-dose dependent in vitro: implications for …

A Fouad, CM Gill, PJ Simner, DP Nicolau… - Journal of …, 2023 - academic.oup.com
Abstract Background Carbapenem-resistant Enterobacterales (CRE) are a public health
concern. Among these isolates, there are reports of isolates that test as cefepime susceptible …

[HTML][HTML] Clinical characteristics and outcomes of carbapenem-resistant Enterobacterales bacteremia in pediatric patients

YC Liu, CY Lu, TY Yen, LY Chang, JM Chen… - Journal of Microbiology …, 2023 - Elsevier
Abstracts Background/purpose Clinical data on carbapenem-resistant Enterobacterales
(CRE) bacteremia in the pediatric population are limited. This study investigated the clinical …

[HTML][HTML] Clinical, microbiological characteristics and predictors of mortality in patients with carbapenemase-producing Enterobacterales bloodstream infections: a …

V Anton-Vazquez, TJ Evans, S Fernando… - Infection Prevention in …, 2023 - Elsevier
Objectives To investigate the clinical, microbiological characteristics and outcomes of
patients with bloodstream infections (BSI) due to carbapenemase-producing …