The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …

An imbalance in microbial homeostasis, referred to as dysbiosis, is critically associated with
the progression of obesity-induced metabolic disorders including type 2 diabetes (T2D) …

Gastroenteropathy is a common complication in diabetes associated with damages to the
enteric nervous system. Systemic low-grade inflammation facilitates neurotoxicity, and …

Irritable Bowel syndrome (IBS) is a highly widespread gastrointestinal disorder whose
symptomatology mainly affect the large intestine. Among the risk factors, psychosocial stress …

Interoceptive information relating to intestinal activity and environmental changes in the gut
lumen is continuously and, generally, subconsciously being relayed to the central nervous …

In order to thoroughly understand pediatric disorders of gut-brain interaction (DGBI), it is
important to look beyond the biomedical causes of these disorders and to consider personal …

Background As “the second brain”, the gastrointestinal tract contains an intrinsic neuronal
network: the Enteric Nervous System (ENS). The ENS governs motility, uid homeostasis, and …

Abdominal pain and discomfort are common symptoms of Inflammatory bowel disease (IBD)
and diagnostic criteria for irritable bowel syndrome (IBS) that significantly impair quality of …