Helicobacter pylori-induced chronic gastritis represents a well-established risk factor for
gastric cancer (GC). However, the mechanism by which chronic inflammation caused by H …

Significance: Pyroptosis is a discovered programmed cell death that is mainly executed by
the gasdermin protein family. Cell swelling and membrane perforation are observed when …

Malignant pleural mesothelioma (MPM) is a lethal and rare cancer, even if its incidence has
continuously increased all over the world. Asbestos exposure leads to the development of …

Oral squamous cell carcinoma (OSCC) is the most frequent type of oral cancer of
multifactorial origin, characterized by histological and clinical manifestations. To date, there …

Tumor immunity is a cycle that begins with the release of antigens from tumor cells and ends
with the destruction of tumor cells. High mobility group box 1 (HMGB1) is a nonhistone …

High mobility group box 1 (HMGB1) has dual functions as a nonhistone nucleoprotein and
an extracellular inflammatory cytokine. In the resting state, HMGB1 is mainly located in the …

Background HMGB1 is a highly conserved nuclear protein widely expressed in mammalian
cells. This study aimed to comprehensively investigate the roles and mechanisms of HMGB1 …

Özet Pankreas Kanseri, hızlı metastaz özelliği ile insidansı ve ölüm oranı yüksek olan ciddi
bir hastalıktır. Pankreas kanserinde temel tedavisel yaklaşım kemoterapi ve radyoterapidir …