[HTML][HTML] New drugs before, during, and after hematopoietic stem cell transplantation for patients with acute myeloid leukemia

R Mohty, R El Hamed, E Brissot, A Bazarbachi… - …, 2023 - ncbi.nlm.nih.gov
The treatment of acute myeloid leukemia (AML) has evolved over the past few years with the
advent of next-generation sequencing. Targeted therapies alone or in combination with low …

[HTML][HTML] Real-world experience with CPX-351 in high-risk acute myeloid leukemia

RM Lemoli, P Montesinos, A Jain - Critical reviews in oncology/hematology, 2023 - Elsevier
Abstract CPX-351, a dual-drug liposomal encapsulation of daunorubicin/cytarabine, was
approved for newly diagnosed therapy-related acute myeloid leukemia (AML) and AML with …

CPX-351 in FLT3-mutated acute myeloid leukemia

C Andrews, V Pullarkat, C Recher - Frontiers in Oncology, 2023 - frontiersin.org
CPX-351, a dual-drug liposomal encapsulation of daunorubicin and cytarabine in a 1: 5
molar ratio, is approved for the treatment of newly diagnosed therapy-related acute myeloid …

Clinical outcome of therapy‐related acute myeloid leukemia patients. Real‐life experience in a University Hospital and a Cancer Center in France

A Belhabri, M Heiblig, S Morisset, L Vila… - Cancer …, 2023 - Wiley Online Library
Background t‐AML occurs after a primary malignancy treatment and retains a poor
prognosis. Aims To determine the impact of primary malignancies, therapeutic strategies …

Clinical outcomes after CPX‐351 in patients with high‐risk acute myeloid leukemia: A comparison with a matched cohort from the Spanish PETHEMA registry

T Bernal, AF Moreno, A De Laiglesia… - Cancer …, 2023 - Wiley Online Library
Background CPX‐351 is approved for the treatment of therapy related acute myeloid
leukemia (t‐AML) and AML with myelodysplastic related changes (MRC‐AML). The benefits …

Multicenter Observational Retrospective Study on Febrile Events in Patients with Acute Myeloid Leukemia Treated with Cpx-351 in “Real-Life”: The SEIFEM …

L Fianchi, F Guolo, F Marchesi, C Cattaneo, M Gottardi… - Cancers, 2023 - mdpi.com
Simple Summary CPX-351 has been approved for the treatment of adults with therapy-
related AML (t-AML) or AML with myelodysplasia-related changes (AML–MRC). The aim of …

[HTML][HTML] Real-world experience with CPX-351 treatment for acute myeloid leukemia in England: an analysis from the National Cancer Registration and Analysis …

A Legg, A Lambova, A Broe, J Levy… - … Lymphoma Myeloma and …, 2023 - Elsevier
Background CPX-351 demonstrated improved overall survival (OS) versus conventional 3+
7 daunorubicin/cytarabine chemotherapy in a registrational phase III study in older patients …

Management of Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia

JP Bewersdorf, AM Zeidan - Pathogenesis and Treatment of Leukemia, 2023 - Springer
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) and therapy-
related AML (t-AML) are often combined under the term secondary AML (sAML) and are …

In the Pipeline: Emerging Therapy for Acute Myeloid Leukaemia

H Gill, A Yip - Pathogenesis and Treatment of Leukemia, 2023 - Springer
Acute myeloid leukaemia (AML) is an aggressive, heterogenous, and age-related
haematological malignancy with dismal prognosis. Conventional therapy for AML consists of …

[HTML][HTML] Secondary Acute Myeloid Leukemia in Myelodysplastic Syndrome Patients Aged Over 60 Years

D Chaudhuri, KI Khan, R Al Shouli, A Allakky… - Cureus, 2023 - ncbi.nlm.nih.gov
In myelodysplastic syndrome (MDS), neoplastic cells originate in hematopoietic stem cells of
the bone marrow, causing dysplasia in multiple cell lines. This may ultimately lead to …