[HTML][HTML] Role of piRNA biogenesis and its neuronal function in the development of neurodegenerative diseases

K Sato, K Takayama, S Inoue - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
and amyotrophic lateral sclerosis (ALS), are caused by neuronal loss and dysfunction …

Identification and targeting of a unique NaV1.7 domain driving chronic pain

K Gomez, HJ Stratton, P Duran… - Proceedings of the …, 2023 - National Acad Sciences
Small molecules directly targeting the voltage-gated sodium channel (VGSC) NaV1. 7 have
not been clinically successful. We reported that preventing the addition of a small ubiquitin …

Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain

HJ Stratton, L Boinon, K Gomez, L Martin, P Duran… - Pain, 2023 - journals.lww.com
Targeting the vascular endothelial growth factor A/neuropili... : PAIN Targeting the vascular
endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain : PAIN International …

Regulación de la expresión de receptores de glicina mediada por la activación o inhibición de la proteína quinasa dependiente de ciclina 5 (Cdk5)

GA González Gómez - 2023 - repositorio.udec.cl
La quinasa dependiente de ciclina 5 (Cdk5) es una enzima que fosforila residuos de serina
o treonina dirigidos por prolina. Cdk5 participa en diferentes etapas del desarrollo del …

[PDF][PDF] PERAN NGF DAN BDNF DALAM MENINGKATKAN PERTAHANAN ANTIOKSIDAN MELALUI AKTIVASI NRF2/ARE PADA REGENERASI SARAF TEPI PASCA …

M Pratiwisitha, R Margiana - LAMBUNG MANGKURAT MEDICAL …, 2023 - fk.ulm.ac.id
ABSTRAK Latar Belakang: Cedera saraf tepi adalah kondisi neurologis yang memberikan
dampak fungsional signifikan pada pasien. Meskipun sistem saraf tepi memiliki potensi …

Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons

MN Tiwari, BE Hall, AT Ton, R Ghetti, A Terse… - Molecular …, 2023 - journals.sagepub.com
Chronic pain is one of the most devastating and unpleasant conditions, associated with
many pathological states. Tissue or nerve injuries induce extensive neurobiological …