Physiological and molecular sex differences in human skeletal muscle in response to exercise training

S Landen, D Hiam, S Voisin, M Jacques… - The Journal of …, 2023 - Wiley Online Library
Sex differences in exercise physiology, such as substrate metabolism and skeletal muscle
fatigability, stem from inherent biological factors, including endogenous hormones and …

Sex differences in muscle protein expression and DNA methylation in response to exercise training

S Landen, M Jacques, D Hiam… - Biology of Sex …, 2023 - Springer
Background Exercise training elicits changes in muscle physiology, epigenomics,
transcriptomics, and proteomics, with males and females exhibiting differing physiological …

Muscle miRNAs are influenced by sex at baseline and in response to exercise

D Hiam, S Landen, M Jacques, S Voisin, S Lamon… - BMC biology, 2023 - Springer
Background Sex differences in microRNA (miRNA) expression profiles have been found
across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body …

Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training.

M Jacques, S Landen, JA Romero, D Hiam… - The FASEB …, 2023 - vuir.vu.edu.au
Exercise is a major beneficial contributor to muscle metabolism, and health benefits
acquired by exercise are a result of molecular shifts occurring across multiple molecular …

Implementation of multiple statistical methods to estimate variability and individual response to training

M Jacques, S Landen, JA Romero, X Yan… - European Journal of …, 2023 - Taylor & Francis
Multiple statistical methods have been proposed to estimate individual responses to
exercise training; yet, the evaluation of these methods is lacking. We compared five of these …

Gynostemma Pentaphyllum Increases Exercise Performance and Alters Mitochondrial Respiration and AMPK in Healthy Males

D Nayyar, X Yan, G Xu, M Shi, AP Garnham, ML Mathai… - Nutrients, 2023 - mdpi.com
This research aimed to determine the effects of Gynostemma pentaphyllum (G.
pentaphyllum) on exercise performance, AMP-activated protein kinase (AMPK), and …

The influence of Sex on microRNA expression in Human Skeletal Muscle

D Hiam, S Landen, M Jacques, S Voisin, S Lamon… - bioRxiv, 2023 - biorxiv.org
Introduction Sex differences in microRNA (miRNA) expression profiles have been found
across multiple tissues. Skeletal muscle is one of the top tissues that underpin sex-based …

Quantifying the ageing methylome: a multi-tissue map in humans

K Seale - 2023 - vuir.vu.edu.au
The epigenome is a dynamic system of chemical modifications that operate to control
chromatin structure and regulate gene activity without altering the underlying DNA …

[PDF][PDF] A transcriptomic approach to the discovery of novel biomarkers of blood doping and training

A Karanikolou - 2023 - research.brighton.ac.uk
Investigating the whole transcriptome or exome is a prevailing approach that is extensively
employed for the discovery phase in biomedical research. Microarray technology is an …

Genomics and biology of exercise, where are we now?

D Hiam, P Jones, Y Pitsiladis… - Clinical Journal of Sport …, 2023 - journals.lww.com
(Clin J Sport Med 2023; 33: e112–e114) Genomics and the biology of exercise is an exciting
research field aiming to understand how genetic variations interact with the environment to …