[HTML][HTML] SIRT1 pathway in Parkinson's disease: a faraway snapshot but so close

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb… - …, 2023 - Springer
Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

[HTML][HTML] A Review of Fibraurea tinctoria and Its Component, Berberine, as an Antidiabetic and Antioxidant

I Purwaningsih, IP Maksum, D Sumiarsa, S Sriwidodo - Molecules, 2023 - mdpi.com
Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia caused
by resistance to insulin action, inadequate insulin secretion, or excessive glucagon …

[HTML][HTML] Obesity prevalence, physical activity, and dietary practices among adults in Saudi Arabia

S Alsulami, M Baig, T Ahmad, N Althagafi… - Frontiers in Public …, 2023 - frontiersin.org
Introduction The current study evaluated obesity prevalence, physical activity, and dietary
practices among Saudi adults in the Makkah region of the Kingdom of Saudi Arabia (KSA) …

Polystyrene microplastics disrupt female reproductive health and fertility via sirt1 modulation in zebrafish (Danio rerio)

P Gupta, A Mahapatra, A Suman, SS Ray… - Journal of Hazardous …, 2023 - Elsevier
Microplastics (MPs) pollution poses an emerging threat to aquatic biota, which could hinder
their physiological processes. Recently various evidence has demonstrated the toxic …

DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice

HJ Sun, JX Tan, XD Shan, ZC Wang, ZY Wu, JS Bian… - Metabolism, 2023 - Elsevier
Abstract Background Na+/K+-ATPase (NKA), an ion pumping enzyme ubiquitously
expressed in various cells, is critically involved in cellular ion homeostasis and signal …

Quercetin ameliorates ferroptosis of rat cardiomyocytes via activation of the SIRT1/p53/SLC7A11 signaling pathway to alleviate sepsis‑induced cardiomyopathy

X Lin, X Zhao, Q Chen, X Wang… - … journal of molecular …, 2023 - spandidos-publications.com
Sepsis‑induced cardiomyopathy (SIC) is a manifestation of multiple organ failure as a result
of sepsis and is a serious threat to life. Here, the effect and mechanisms of quercetin (QUE) …

[HTML][HTML] Protective effects of melatonin against physical injuries to testicular tissue: A systematic review and meta-analysis of animal models

N Dehdari Ebrahimi, S Shojaei-Zarghani… - Frontiers in …, 2023 - frontiersin.org
Background Modern societies face infertility as a global challenge. There are certain
environmental conditions and disorders that damage testicular tissue and may cause male …

[HTML][HTML] Improvement in ovarian function following fecal microbiota transplantation from high-laying rate breeders

S Cao, D Guo, H Yin, X Ding, S Bai, Q Zeng, J Liu… - Poultry Science, 2023 - Elsevier
The underlying mechanism between the gut microbiota and reproductive function is not yet
well-known. This study was conducted to investigate the effect of the administration of fecal …

[HTML][HTML] Captivating colors, crucial roles: Astaxanthin's antioxidant impact on Fish oxidative stress and Reproductive Performance

Y Shastak, W Pelletier - Animals, 2023 - mdpi.com
Simple Summary Oxidative stress represents a significant threat to fish health, resulting in
cellular damage and a host of health challenges. Astaxanthin, a powerful antioxidant, plays …

[HTML][HTML] Regulation of SIRT1 in ovarian function: PCOS treatment

X Li, Y He, S Wu, P Zhang, M Gan, L Chen… - Current Issues in …, 2023 - mdpi.com
The sirtuin family, a group of NAD+-dependent class 3 histone deacetylases (HDACs), was
extensively studied initially as a group of longevity genes that are activated in caloric …