The regulative effect and repercussion of probiotics and prebiotics on osteoporosis: involvement of brain-gut-bone axis
YW Zhang, MM Cao, YJ Li, GC Dai, PP Lu… - Critical reviews in …, 2023 - Taylor & Francis
Osteoporosis (OP) is a systemic disease characterized by decreased bone mass and
degeneration of bone microstructure. In recent years, more and more researches have …
degeneration of bone microstructure. In recent years, more and more researches have …
The protective and pathogenic role of Th17 cell plasticity and function in the tumor microenvironment
Y Pan, W Yang, B Tang, X Wang, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
At the turn of the century, researchers discovered a unique subtype of T helper cells that
secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both …
secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both …
Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer
JX Han, ZH Tao, JL Wang, L Zhang, CY Yu… - Nature …, 2023 - nature.com
Epidemiological studies have indicated an association between statin use and reduced
incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a …
incidence of colorectal cancer (CRC), and work in preclinical models has demonstrated a …
Interaction of tumor‑associated macrophages with stromal and immune components in solid tumors: Research progress
A Kazakova, T Sudarskikh… - International …, 2023 - spandidos-publications.com
Tumor‑associated macrophages (TAMs) are crucial cells of the tumor microenvironment
(TME), which belong to the innate immune system and regulate primary tumor growth …
(TME), which belong to the innate immune system and regulate primary tumor growth …
Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α–Mediated Inflammation
Y Lou, S Jiang, M Song, H Wang, M Han… - The Journal of …, 2023 - journals.aai.org
Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal
immune response, and IEC dysfunction has been linked to multiple inflammatory diseases …
immune response, and IEC dysfunction has been linked to multiple inflammatory diseases …
BAP31 Knockout in Macrophages Affects CD4+T Cell Activation through Upregulation of MHC Class II Molecule
B Zhao, L Sun, Q Yuan, Z Hao, F An, W Zhang… - International Journal of …, 2023 - mdpi.com
The differentiation of CD4+ T cells is a crucial component of the immune response. The
spleen and thymus, as immune organs, are closely associated with the differentiation and …
spleen and thymus, as immune organs, are closely associated with the differentiation and …
The role of T cells and shared genes in psoriasis and inflammatory bowel disease based on single-cell RNA and comprehensive analysis
X Liang, Z Peng, Y Deng, X Lin, R Chen, Y Niu, W Lin… - Immunobiology, 2023 - Elsevier
Psoriasis and inflammatory bowel disease (IBD) have a similar etiology, including abnormal
activation of T cells. Differentially expressed genes (DEGs) analysis was used to search for …
activation of T cells. Differentially expressed genes (DEGs) analysis was used to search for …
Targeting inflammatory macrophages rebuilds therapeutic efficacy of DOT1L inhibition in hepatocellular carcinoma
YB Yang, CY Wu, XY Wang, J Deng, WJ Cao, YZ Tang… - Molecular Therapy, 2023 - cell.com
Epigenetic reprogramming is a promising therapeutic strategy for aggressive cancers, but its
limitations in vivo remain unclear. Here, we showed, in detailed studies of data regarding …
limitations in vivo remain unclear. Here, we showed, in detailed studies of data regarding …
Murine TBK1 Is Required by Flt3+ Leukemia Stem Cells Yet Dispensable in Homeostatic Hematopoiesis
AP Runde - 2023 - search.proquest.com
The TANK-binding kinase 1 (TBK1) is a cytoplasmic, serine/threonine kinase and a critical
activator of the innate immune system. Reports have implicated TBK1 as a promoter of …
activator of the innate immune system. Reports have implicated TBK1 as a promoter of …
Paneth Cells Regulate Innate Immune Cell Populations, and Contribute to Allergy and Obesity Disease Progression
MR Joldrichsen - 2023 - rave.ohiolink.edu
Alteration of the gut microbiota has been linked to non-infectious diseases such as obesity
and allergy. However, mechanisms linking dysbiosis with non-infectious diseases or …
and allergy. However, mechanisms linking dysbiosis with non-infectious diseases or …