Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …

As the most common non-Hodgkin lymphoma subtype, diffuse large B-cell lymphoma
(DLBCL) incidence patterns generally parallel that for NHL overall. Globally, DLBCL …

Background Genomic regions identified by genome-wide association studies (GWAS) for
bladder cancer risk provide new insights into etiology. Objective To identify new …

On a global scale, the incidence and mortality rates of lung cancer are gradually increasing
year by year. A number of bad habits and environmental factors are associated with lung …

Integrating genomic data of multiple cancers allows de novo cancer grouping and
elucidating the shared genetic basis across cancers. Here, we conduct the pan-cancer and …

Esophageal squamous cell carcinoma (ESCC) has a high disease burden in sub-Saharan
Africa and has a very poor prognosis. Genome-wide association studies (GWASs) of ESCC …

Genome-wide polygenic risk scores (GW-PRSs) have been reported to have better
predictive ability than PRSs based on genome-wide significance thresholds across …

Several reports have described a worldwide increasing incidence of chronic lymphocytic
leukemia (CLL) dating back seven-eight decades. While genetic susceptibility would be an …

Pleiotropy, which consists of a single gene or allelic variant affecting multiple unrelated
traits, is common across cancers, with evidence for genome‐wide significant loci shared …

Many studies have shown that the distributions of the genomic, nucleotide, and epigenetic
contexts of somatic variants in tumors are informative of cancer etiology. Recently, a new …