Long COVID-19 pathophysiology: what do we know so far?

NR Tziolos, P Ioannou, S Baliou, DP Kofteridis - Microorganisms, 2023 - mdpi.com
Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad
clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath …

Bone fragility during the COVID-19 pandemic: the role of macro-and micronutrients

A Moretti, S Liguori, M Paoletta… - Therapeutic …, 2023 - journals.sagepub.com
Bone fragility is the susceptibility to fracture due to poor bone strength. This condition is
usually associated with aging, comorbidities, disability, poor quality of life, and increased …

Stem Cell‐Niche Engineering via Multifunctional Hydrogel Potentiates Stem Cell Therapies for Inflammatory Bone Loss

G Li, Z Li, L Li, S Liu, P Wu, M Zhou, C Li… - Advanced Functional …, 2023 - Wiley Online Library
Effective therapies capable of simultaneously inhibiting inflammation and promoting bone
healing remain to be developed for inflammatory bone disease. Stem cell therapies hold …

BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism

J Du, Y Liu, X Wu, J Sun, J Shi, H Zhang… - Nature …, 2023 - nature.com
Abstract Bromodomain-containing protein 9 (BRD9), a component of non-canonical BAF
chromatin remodeling complex, has been identified as a critical therapeutic target in …

[HTML][HTML] Osteoporosis and Covid-19: Detected similarities in bone lacunar-level alterations via combined AI and advanced synchrotron testing

F Buccino, L Zagra, E Longo, L D'Amico, G Banfi… - Materials & Design, 2023 - Elsevier
While advanced imaging strategies have improved the diagnosis of bone-related
pathologies, early signs of bone alterations remain difficult to detect. The Covid-19 …

Development of nanozymes for promising alleviation of COVID-19-associated arthritis

D Li, B Zhao, P Zhuang, X Mei - Biomaterials Science, 2023 - pubs.rsc.org
The COVID-19 pandemic caused by SARS-CoV-2 has been identified as a culprit in the
development of a variety of disorders, including arthritis. Although the emergence of arthritis …

Moderate COVID‐19 disease is associated with reduced bone turnover

K Kerschan‐Schindl, P Dovjak… - Journal of Bone and …, 2023 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV2) infection has been
associated with musculoskeletal manifestations, including a negative effect on bone health …

Correlations of Myeloperoxidase (MPO), Adenosine deaminase (ADA), C–C motif chemokine 22 (CCL22), Tumour necrosis factor alpha (TNFα) and Interleukin-6 (IL-6 …

KHY Chiu, CCY Yip, RWS Poon, KH Leung… - Emerging microbes & …, 2023 - Taylor & Francis
Cytokine dynamics in patients with coronavirus disease 2019 (COVID-19) have been
studied in blood but seldomly in respiratory specimens. We studied different cell markers …

Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 on metabolic unhealthy obese patients

T Huang, N Jiang, Y Song, H Pan, A Du… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: The severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) has
posed a significant challenge to individuals' health. Increasing evidence shows that patients …

Intranasal infection by SARS-CoV-2 Omicron variants can induce inflammatory brain damage in newly weaned hamsters

C Li, W Song, JFW Chan, Y Chen, F Liu… - Emerging Microbes & …, 2023 - Taylor & Francis
Children infected by SARS-CoV-2 Omicron variant may develop neurological complications.
To study the pathogenesis in the growing brain, we intranasally challenged newly-weaned …