Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma

M Rosellini, A Marchetti, V Mollica, A Rizzo… - Nature Reviews …, 2023 - nature.com
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of
immunotherapy agents by regulatory agencies. However, objective and durable responses …

Artificial intelligence for predictive biomarker discovery in immuno-oncology: a systematic review

A Prelaj, V Miskovic, M Zanitti, F Trovo, C Genova… - Annals of …, 2023 - Elsevier
Background The widespread use of Immune checkpoint-inhibitors (ICI) has revolutionised
treatment of multiple cancer types. However, selecting patients who may benefit from ICI …

State of the art: Multidisciplinary management of oligometastatic renal cell carcinoma

S Dason, K Lacuna, R Hannan, EA Singer… - American Society of …, 2023 - ascopubs.org
Oligometastatic renal cell carcinoma (OM-RCC) refers to patients who have limited (typically
up to 5) metastatic lesions. Although management principles may overlap, OM-RCC is …

[HTML][HTML] Complete response in metastatic clear cell renal cell carcinoma patients treated with immune-checkpoint inhibitors: remission or healing? How to improve …

J Thouvenin, C Masson, P Boudier, D Maillet… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy-based combinations represent the front-line standard of
care for metastatic clear cell renal cell carcinoma (mccRCC) patients. These combinations …

Real‐world outcomes of 18,186 metastatic solid tumor outpatients: Baseline blood cell counts correlate with survival after immune checkpoint inhibitor therapy

JH Goldschmidt, LN Chou, PK Chan, L Chen… - Cancer …, 2023 - Wiley Online Library
Background Patient survival in advanced/metastatic melanoma, non‐small cell lung cancer
(NSCLC), and renal cell carcinoma (RCC) has improved with immune checkpoint inhibitors …

Early increases in blood pressure and major adverse cardiovascular events in patients with renal cell carcinoma and thyroid cancer treated with VEGFR TKIs

V Narayan, T Liu, Y Song, J Mitchell, JR Sicks… - Journal of the National …, 2023 - jnccn.org
Background: Although VEGFR tyrosine kinase inhibitors (TKIs) are a preferred systemic
treatment approach for patients with advanced renal cell carcinoma (RCC) and thyroid …

[HTML][HTML] SEOM SOGUG clinical guideline for treatment of kidney cancer (2022)

MJ Méndez-Vidal, M Lázaro Quintela… - Clinical and …, 2023 - Springer
Renal cancer is the seventh most common cancer in men and the tenth in women. The aim
of this article is to review the diagnosis, treatment, and follow-up of renal carcinoma …

[HTML][HTML] Second-Line Treatment of Metastatic Renal Cell Carcinoma in the Era of Predictive Biomarkers

AI Parosanu, C Baston, IM Stanciu, CF Parlog, C Nitipir - Diagnostics, 2023 - mdpi.com
Background: Over the past few years, significant advancements have been achieved in the
front-line treatment of metastatic renal cell carcinomas (mRCCs). However, most patients will …

[HTML][HTML] Artificial intelligence-based prediction of overall survival in metastatic renal cell carcinoma

E Barkan, C Porta, S Rabinovici-Cohen… - Frontiers in …, 2023 - frontiersin.org
Background and objectives Investigations of the prognosis are vital for better patient
management and decision-making in patients with advanced metastatic renal cell …

Comparative real-world survival outcomes of metastatic papillary and clear cell renal cell carcinoma treated with immunotherapy, targeted therapy, and combination …

C Riveros, S Ranganathan, J Xu, C Chang… - … Oncology: Seminars and …, 2023 - Elsevier
Introduction While there are a plethora of studies supporting novel treatment approaches in
metastatic clear cell renal cell carcinoma (ccRCC), much of the data used to inform care of …