Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

The discovery of miRNAs and their role in disease represent a significant breakthrough that
has stimulated and propelled research on miRNAs as targets for diagnosis and therapy …

The abdominal aortic aneurysm (AAA) is characterized by segmental expansion of the
abdominal aorta and a high mortality rate. The characteristics of AAA suggest that apoptosis …

Aortic stiffness is an independent risk factor for aortic diseases such as aortic dissection
which commonly occurred with aging and hypertension. Chemokine receptor CXCR6 is …

Circulating serum miRNA are increasingly used as biomarkers and potential treatment
targets in several clinical scenarios, including cardiovascular diseases. However, the current …

Background: Genome-wide association studies have reported 23 gene loci related to
abdominal aortic aneurysm (AAA)—a potentially lethal condition characterized by a …

Aims Abdominal aortic aneurysm (AAA) is a common cardiovascular disease with a strong
correlation to smoking, although underlying mechanisms have been minimally explored …

An aortic aneurysm (AA) is defined as focal aortic dilation that occurs mainly with older age
and with chronic inflammation associated with atherosclerosis. The aneurysmal wall is a …

The global population is estimated to reach 9.8 billion by 2050, of which 2.1 billion will
comprise individuals above 60 years of age. As the number of elderly is estimated to double …

It has been demonstrated that noncoding RNAs have significant physiological and
pathological roles. Modulation of noncoding RNAs may offer therapeutic approaches as per …