[HTML][HTML] Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets
J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …
challenge to effective treatment. Cancer stem cells and their markers have become key …
[HTML][HTML] Insight into microRNAs' involvement in hematopoiesis: current standing point of findings
SM Nassiri, N Ahmadi Afshar, P Almasi - Stem Cell Research & Therapy, 2023 - Springer
Hematopoiesis is a complex process in which hematopoietic stem cells are differentiated
into all mature blood cells (red blood cells, white blood cells, and platelets). Different …
into all mature blood cells (red blood cells, white blood cells, and platelets). Different …
[HTML][HTML] HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation
Identification of factors that regulate chromatin condensation is important for understanding
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …
[HTML][HTML] Can CD133 Be Regarded as a Prognostic Biomarker in Oncology: Pros and Cons
A Gisina, Y Kim, K Yarygin, A Lupatov - International Journal of Molecular …, 2023 - mdpi.com
The CD133 cell membrane glycoprotein, also termed prominin-1, is expressed on some of
the tumor cells of both solid and blood malignancies. The CD133-positive tumor cells were …
the tumor cells of both solid and blood malignancies. The CD133-positive tumor cells were …
Loss of Prom1 impairs autophagy and promotes epithelial‐mesenchymal transition in mouse retinal pigment epithelial cells
S Bhattacharya, J Yin, W Huo… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract Mutations in the Prominin‐1 (Prom1) gene disrupt photoreceptor disk
morphogenesis, leading to macular dystrophies. We have shown that human retinal pigment …
morphogenesis, leading to macular dystrophies. We have shown that human retinal pigment …
[HTML][HTML] CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity
MJ Ford, K Harwalkar, H Kazemdarvish… - Biology …, 2023 - journals.biologists.com
The epithelium lining the oviduct or fallopian tube consists of multiciliated and secretory
cells, which support fertilization and preimplantation development, however, its homeostasis …
cells, which support fertilization and preimplantation development, however, its homeostasis …
[HTML][HTML] Insights into Common Octopus (Octopus vulgaris) Ink Proteome and Bioactive Peptides Using Proteomic Approaches
The common octopus (Octopus vulgaris) is nowadays the most demanded cephalopod
species for human consumption. This species was also postulated for aquaculture …
species for human consumption. This species was also postulated for aquaculture …
[HTML][HTML] Molecular Regulation of Autophagy and Asymmetric Cell Division by Cancer Stem Cell Marker CD133
H Izumi, Y Kaneko, A Nakagawara - Cells, 2023 - mdpi.com
CD133, also called prominin-1, is widely known as a cancer stem cell marker, and its high
expression correlates with a poor prognosis in many cancers. CD133 was originally …
expression correlates with a poor prognosis in many cancers. CD133 was originally …
Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP‐A
Extracellular vesicles (EVs) influence cell phenotypes and functions via protein, nucleic acid,
and lipid cargoes. EVs are heterogeneous, due to diverse biogenesis mechanisms that …
and lipid cargoes. EVs are heterogeneous, due to diverse biogenesis mechanisms that …
Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice
H Matsukuma, Y Kobayashi, S Oka… - Reproductive …, 2023 - Wiley Online Library
Purpose Spermatogenesis is a complex process orchestrated by several essential genes.
Prominin‐1 (Prom1/PROM1) is a gene that is expressed in the testis but with a poorly …
Prominin‐1 (Prom1/PROM1) is a gene that is expressed in the testis but with a poorly …