[HTML][HTML] Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets

J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …

[HTML][HTML] Insight into microRNAs' involvement in hematopoiesis: current standing point of findings

SM Nassiri, N Ahmadi Afshar, P Almasi - Stem Cell Research & Therapy, 2023 - Springer
Hematopoiesis is a complex process in which hematopoietic stem cells are differentiated
into all mature blood cells (red blood cells, white blood cells, and platelets). Different …

[HTML][HTML] HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation

N Kuwayama, T Kujirai, Y Kishi, R Hirano… - Nature …, 2023 - nature.com
Identification of factors that regulate chromatin condensation is important for understanding
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …

[HTML][HTML] Can CD133 Be Regarded as a Prognostic Biomarker in Oncology: Pros and Cons

A Gisina, Y Kim, K Yarygin, A Lupatov - International Journal of Molecular …, 2023 - mdpi.com
The CD133 cell membrane glycoprotein, also termed prominin-1, is expressed on some of
the tumor cells of both solid and blood malignancies. The CD133-positive tumor cells were …

Loss of Prom1 impairs autophagy and promotes epithelial‐mesenchymal transition in mouse retinal pigment epithelial cells

S Bhattacharya, J Yin, W Huo… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract Mutations in the Prominin‐1 (Prom1) gene disrupt photoreceptor disk
morphogenesis, leading to macular dystrophies. We have shown that human retinal pigment …

[HTML][HTML] CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity

MJ Ford, K Harwalkar, H Kazemdarvish… - Biology …, 2023 - journals.biologists.com
The epithelium lining the oviduct or fallopian tube consists of multiciliated and secretory
cells, which support fertilization and preimplantation development, however, its homeostasis …

[HTML][HTML] Insights into Common Octopus (Octopus vulgaris) Ink Proteome and Bioactive Peptides Using Proteomic Approaches

MAS Imran, M Carrera, S Pérez-Polo, J Pérez, L Barros… - Marine Drugs, 2023 - mdpi.com
The common octopus (Octopus vulgaris) is nowadays the most demanded cephalopod
species for human consumption. This species was also postulated for aquaculture …

[HTML][HTML] Molecular Regulation of Autophagy and Asymmetric Cell Division by Cancer Stem Cell Marker CD133

H Izumi, Y Kaneko, A Nakagawara - Cells, 2023 - mdpi.com
CD133, also called prominin-1, is widely known as a cancer stem cell marker, and its high
expression correlates with a poor prognosis in many cancers. CD133 was originally …

Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP‐A

B Barman, M Ramirez, TR Dawson, Q Liu… - …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) influence cell phenotypes and functions via protein, nucleic acid,
and lipid cargoes. EVs are heterogeneous, due to diverse biogenesis mechanisms that …

Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

H Matsukuma, Y Kobayashi, S Oka… - Reproductive …, 2023 - Wiley Online Library
Purpose Spermatogenesis is a complex process orchestrated by several essential genes.
Prominin‐1 (Prom1/PROM1) is a gene that is expressed in the testis but with a poorly …