Tissue growth and remodeling (G&R) is often central to disease etiology and progression, so
understanding G&R is essential for understanding disease and developing effective …

Abdominal aortic aneurysm (AAA) disease, the local enlargement of the infrarenal aorta, is a
serious condition that causes many deaths, especially in men exceeding 65 years of age …

9p21. 3 locus polymorphisms have the strongest correlation with coronary artery disease,
but as a noncoding locus, disease connection is enigmatic. The lncRNA ANRIL found in …

Collagen as the main protein in Extra Cellular Matrix (ECM) is the main load-bearing
component of fibrous tissues. Nanostructure and architecture of collagen fibrils play an …

Inspired by biology and engineered soft active material systems, we propose a new
constitutive formulation for a soft material consisting of soft contractile fibers embedded in a …

Multiscale mechanical models in biomaterials research have largely relied on simplifying the
microstructure in order to make large-scale simulations tractable. The microscale …

Non-invasive microstructural characterisation has the potential to determine the stability, or
lack thereof, of atherosclerotic plaques and ultimately aid in better assessing plaques' risk to …

Understanding how the homeostatic stress state can be reached in arterial tissues can
provide new insights into vascular physiology. Even though the function of maintaining …

To improve the current treatment for vascular diseases, such as vascular grafts, intravascular
stents, and balloon angioplasty intervention, the evaluation of the native blood vessel …

Aortic dissection is a complex, intramural, and dynamic condition involving multiple
mechanisms, hence, difficult to observe. In the present study, a controlled in vitro aortic …