Hybrid discrete-continuum multiscale model of tissue growth and remodeling
Tissue growth and remodeling (G&R) is often central to disease etiology and progression, so
understanding G&R is essential for understanding disease and developing effective …
understanding G&R is essential for understanding disease and developing effective …
A quarter of a century biomechanical rupture risk assessment of abdominal aortic aneurysms. Achievements, clinical relevance, and ongoing developments
Abdominal aortic aneurysm (AAA) disease, the local enlargement of the infrarenal aorta, is a
serious condition that causes many deaths, especially in men exceeding 65 years of age …
serious condition that causes many deaths, especially in men exceeding 65 years of age …
Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity
JM Mayner, EM Masutani… - Proceedings of the …, 2023 - National Acad Sciences
9p21. 3 locus polymorphisms have the strongest correlation with coronary artery disease,
but as a noncoding locus, disease connection is enigmatic. The lncRNA ANRIL found in …
but as a noncoding locus, disease connection is enigmatic. The lncRNA ANRIL found in …
The importance of consideration of collagen cross-links in computational models of collagen-based tissues
M Mohammadkhah, S Klinge - Journal of the Mechanical Behavior of …, 2023 - Elsevier
Collagen as the main protein in Extra Cellular Matrix (ECM) is the main load-bearing
component of fibrous tissues. Nanostructure and architecture of collagen fibrils play an …
component of fibrous tissues. Nanostructure and architecture of collagen fibrils play an …
Constitutive formulations for intrinsic anisotropy in soft electroelastic materials
Y Li, NC Goulbourne - Scientific Reports, 2023 - nature.com
Inspired by biology and engineered soft active material systems, we propose a new
constitutive formulation for a soft material consisting of soft contractile fibers embedded in a …
constitutive formulation for a soft material consisting of soft contractile fibers embedded in a …
The non-affine fiber network solver: A multiscale fiber network material model for finite-element analysis
Multiscale mechanical models in biomaterials research have largely relied on simplifying the
microstructure in order to make large-scale simulations tractable. The microscale …
microstructure in order to make large-scale simulations tractable. The microscale …
Microstructural and mechanical insight into atherosclerotic plaques: an ex vivo DTI study to better assess plaque vulnerability
Non-invasive microstructural characterisation has the potential to determine the stability, or
lack thereof, of atherosclerotic plaques and ultimately aid in better assessing plaques' risk to …
lack thereof, of atherosclerotic plaques and ultimately aid in better assessing plaques' risk to …
A novel constitutive model considering the role of elastic lamellae'structural heterogeneity in homogenizing transmural stress distribution in arteries
T Sigaeva, Y Zhang - Journal of the Royal Society …, 2023 - royalsocietypublishing.org
Understanding how the homeostatic stress state can be reached in arterial tissues can
provide new insights into vascular physiology. Even though the function of maintaining …
provide new insights into vascular physiology. Even though the function of maintaining …
Non-destructive 3D characterization of the blood vessel wall microstructure in different species and blood vessel types using contrast-enhanced microCT and …
L Leyssens, T Balcaen, M Pétré, NB Ayllón… - Acta Biomaterialia, 2023 - Elsevier
To improve the current treatment for vascular diseases, such as vascular grafts, intravascular
stents, and balloon angioplasty intervention, the evaluation of the native blood vessel …
stents, and balloon angioplasty intervention, the evaluation of the native blood vessel …
In situ visualization of aortic dissection propagation in notched rabbit aorta using synchrotron X-ray tomography
Aortic dissection is a complex, intramural, and dynamic condition involving multiple
mechanisms, hence, difficult to observe. In the present study, a controlled in vitro aortic …
mechanisms, hence, difficult to observe. In the present study, a controlled in vitro aortic …