Overactive bladder syndrome with and without urinary incontinence and related conditions,
signs, and disorders such as detrusor overactivity, neurogenic lower urinary tract …

Resiniferatoxin (RTX) is an ultrapotent capsaicin analog with a unique spectrum of
pharmacological actions. The therapeutic window of RTX is broad, allowing for the full …

The urothelium, which covers the inner surface of the bladder, is continuously exposed to a
complex physical environment where it is stimulated by, and responds to, a wide range of …

Botulinum toxins (Botn) are potent naturally occurring neurotoxins with properties that when
applied in a controlled manner have, for over half a century, been utilised as a therapy for a …

Intravesical drug therapy for neurogenic bladder is currently limited to oxybutynin where
higher drug levels can be achieved with lower side effect profiles than via the oral route. The …