Ion channels of the sarcolemma and intracellular organelles in Duchenne muscular dystrophy: a role in the dysregulation of ion homeostasis and a possible target for …

MV Dubinin, KN Belosludtsev - International Journal of Molecular …, 2023 - mdpi.com
Duchenne muscular dystrophy (DMD) is caused by the absence of the dystrophin protein
and a properly functioning dystrophin-associated protein complex (DAPC) in muscle cells …

Is the fundamental pathology in Duchenne's muscular dystrophy caused by a failure of glycogenolysis–glycolysis in costameres?

V Nesari, S Balakrishnan, U Nongthomba - Journal of genetics, 2023 - Springer
Duchenne muscular dystrophy (DMD) is the most common form of progressive childhood
muscular dystrophy associated with weakness of limbs, loss of ambulation, heart weakness …

Profiling of chromatin accessibility in pigs across multiple tissues and developmental stages

J Bai, Y Lin, J Zhang, Z Chen, Y Wang, M Li… - International Journal of …, 2023 - mdpi.com
The study of chromatin accessibility across tissues and developmental stages is essential for
elucidating the transcriptional regulation of various phenotypes and biological processes …

Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote …

JL McCourt, KM Stearns-Reider, H Mamsa, P Kannan… - Skeletal muscle, 2023 - Springer
Background The dystrophin-glycoprotein complex (DGC) is a critical adhesion complex of
the muscle cell membrane, providing a mechanical link between the extracellular matrix …

Curcumin Administration Improves Force of mdx Dystrophic Diaphragm by Acting on Fiber-Type Composition, Myosin Nitrotyrosination and SERCA1 Protein Levels

L Gorza, E Germinario, M Vitadello, I Guerra, F De Majo… - Antioxidants, 2023 - mdpi.com
The vegetal polyphenol curcumin displays beneficial effects against skeletal muscle
derangement induced by oxidative stress, disuse or aging. Since oxidative stress and …

Hypochlorous acid exposure impairs skeletal muscle function and Ca2+ signalling: implications for Duchenne muscular dystrophy pathology

TA Lea, PM Panizza, PG Arthur… - The Journal of …, 2023 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease characterised by severe
muscle wasting. The mechanisms underlying the DMD pathology likely involve the …

Eccentric contraction-induced strength loss in dystrophin-deficient muscle: Preparations, protocols, and mechanisms

L Kiriaev, CW Baumann, A Lindsay - Journal of General Physiology, 2023 - rupress.org
The absence of dystrophin hypersensitizes skeletal muscle of lower and higher vertebrates
to eccentric contraction (ECC)-induced strength loss. Loss of strength can be accompanied …

[PDF][PDF] Age Dependent Changes of Ca2+ Handling Proteins in the Tibialis Anterior of Dystrophic Skeletal Muscle

MA Mann - 2023 - ourarchive.otago.ac.nz
Abstract Duchenne Muscular Dystrophy (DMD) is a prevalent variant of muscular dystrophy
affecting approximately 1 in 3500 male infants. This disorder stems from mutations in the …

Exploration of the Mitochondria as a Potential Therapeutic Target in Duchenne Muscular Dystrophy

CA Bellissimo - 2023 - yorkspace.library.yorku.ca
Duchenne muscular dystrophy (DMD) is a fatal muscle wasting condition resulting from the
loss of the structural protein dystrophin. The disease is characterized by severe muscle …

Possible Synergistic Effect of Platelet Rich Plasma and Losartan on Experimentally Induced Skeletal Muscle Injury in Adult Male Albino Rats: A Histological and an …

AH Neanaa, M El-Heneidy, HM Khalifa… - Egyptian Journal of …, 2023 - journals.ekb.eg
Introduction: Minimization of the disability after skeletal muscle injuries is still a challenge.
Understanding of the contribution of growth factors has sparked a lot of interest in platelet …