Designing tailored thiosemicarbazones with bespoke properties: The styrene moiety imparts potent activity, inhibits heme center oxidation, and results in a novel “ …
M Dharmasivam, B Kaya, T Wijesinghe… - Journal of Medicinal …, 2023 - ACS Publications
A novel, potent, and selective antitumor agent, namely (E)-3-phenyl-1-(2-pyridinyl)-2-propen-
1-one 4, 4-dimethyl-3-thiosemicarbazone (PPP44mT), and its analogues were synthesized …
1-one 4, 4-dimethyl-3-thiosemicarbazone (PPP44mT), and its analogues were synthesized …
Recent advances and therapeutic journey of pyridine-based Cu (II) complexes as potent anticancer agents: a review (2015–2022)
M Alshamrani - Journal of Coordination Chemistry, 2023 - Taylor & Francis
Pyridine derivatives are heterocyclic compounds that play a significant role in various fields.
Pyridine derivatives have excellent biological activities such as antiviral, antiarthritic …
Pyridine derivatives have excellent biological activities such as antiviral, antiarthritic …
Structures and Properties of a Series of High-Spin [CoII2] Complexes Supported by Ancillary Benzoate, Ortho-Hydroxybenzoate, and Para-Hydroxybenzoate …
A new series of high-spin [CoII2] complexes [Co2 (cpdp)(μ-O2CC6H5)](1),[Co2 (cpdp)(μ-o-
O2CC6H4 (OH))]· H2O (2), and [Co2 (cpdp)(μ-p-O2CC6H4 (OH))]· 5H2O (3) of the …
O2CC6H4 (OH))]· H2O (2), and [Co2 (cpdp)(μ-p-O2CC6H4 (OH))]· 5H2O (3) of the …
Synthesis, cytotoxicity and DNA binding of novel Ni (II), Co (II) and Zn (II) complexes bearing pyrimidinyl hydrazone ligand
J Yuan, JY Song, HH Yang, HR Lan, AP Xing… - Journal of Molecular …, 2023 - Elsevier
To develop efficient new antitumor agents, Ni (II), Co (II) and Zn (II) complexes 1–3 derived
from 2-((2-pyrimidin-2-yl) hydrazono) methyl) quinoline (HL) were prepared and structurally …
from 2-((2-pyrimidin-2-yl) hydrazono) methyl) quinoline (HL) were prepared and structurally …
Investigation (IR, UV-visible, fluorescence, X-ray diffraction and thermogravimetric) studies of Mn (II), Fe (III) and Cr (III) complexes of thiosemicarbazone derived from …
Trivalent chromium, iron and divalent manganese complexes of thiosemicarbazone ligand
(NaH 3 PyTSC) were synthesized. The complexes were considered by analytical and …
(NaH 3 PyTSC) were synthesized. The complexes were considered by analytical and …
Copper (II) complex enhanced chemodynamic therapy through GSH depletion and autophagy flow blockade
WY Shen, CP Jia, LY Liao, LL Chen, CC Yuan… - Dalton …, 2023 - pubs.rsc.org
Three copper (II) complexes C1–C3 were synthesized and fully characterized as
chemodynamic therapy (CDT) anticancer agents. C1–C3 showed greater cytotoxicity than …
chemodynamic therapy (CDT) anticancer agents. C1–C3 showed greater cytotoxicity than …
Deciphering the Mechanism of MRSA Targeting Copper(II) Complexes of NN2 Pincer-Type Ligands
WHO lists AMR as one of the top ten global public health issues. Therefore, constant effort is
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …
needed to develop more efficient antimicrobial drugs. As a result, earth-abundant transition …
Synthesis, Characterization, DNA/HSA Interaction, and Cytotoxic Activity of a Copper (II) Thiolate Schiff Base Complex and Its Corresponding Water-Soluble Stable …
A Cu (II) thiolato complex [CuL (imz)](1)(H2L= o-HOC6H4C (H)═ NC6H4SH-o) and the
corresponding water-soluble stable sulfinato–O complex [CuL′(imz)](2)(H2L′= o …
corresponding water-soluble stable sulfinato–O complex [CuL′(imz)](2)(H2L′= o …
Water-soluble copper (II) 5-fluorouracil complexes bearing polypyridyl co-ligands: synthesis, structures and anticancer activity
Five newly synthesized copper (II) 5-fluorouracil (5-FU) complexes of polypyridyl co-ligands
with good solubility in water, namely [CuCl (5-FU)(bpy)(DMSO)](1),[Cu (5-FU)(phen) 2](5 …
with good solubility in water, namely [CuCl (5-FU)(bpy)(DMSO)](1),[Cu (5-FU)(phen) 2](5 …
Exploring the Biological Properties of Zn(II) Bisthiosemicarbazone Helicates
S Fernández-Fariña, I Velo-Heleno… - International journal of …, 2023 - mdpi.com
The design of artificial helicoidal molecules derived from metal ions with biological
properties is one of the objectives within metallosupramolecular chemistry. Herein, we report …
properties is one of the objectives within metallosupramolecular chemistry. Herein, we report …