[HTML][HTML] Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies
ME Bahar, HJ Kim, DR Kim - Signal transduction and targeted therapy, 2023 - nature.com
Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality,
underscores the urgent need for enhanced insights into the molecular and cellular …
underscores the urgent need for enhanced insights into the molecular and cellular …
Recent developments and challenges in molecular-targeted therapy of non-small-cell lung cancer
Treatment of lung cancer with conventional therapies, which include radiation, surgery, and
chemotherapy results in multiple undesirable adverse or side effects. The major clinical …
chemotherapy results in multiple undesirable adverse or side effects. The major clinical …
[HTML][HTML] The role of miR-128 in cancer development, prevention, drug resistance, and immunotherapy
A growing body of evidence has revealed that microRNA (miRNA) expression is
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …
[HTML][HTML] CC-115 mediates GSDME-dependent pyroptosis in lung adenocarcinoma through the akt/bax pathway
T Zhang, MQ Liu, GS Xie, DM Wu, PW Luo, T Liu… - Journal of …, 2023 - ncbi.nlm.nih.gov
Chemotherapeutic agents remain the first-line treatment for solid tumors, including lung
cancer, but chemotherapy resistance is hampering global efforts to treat this disease. CC …
cancer, but chemotherapy resistance is hampering global efforts to treat this disease. CC …
Role of exosomal miRNA in chemotherapy resistance of Colorectal cancer: A systematic review
The third most common malignancy has been identified as Colorectal cancer (CRC) that
conducive to death in most cases. Chemoresistance is a common obstacle to CRC …
conducive to death in most cases. Chemoresistance is a common obstacle to CRC …
[HTML][HTML] circ_0000376 knockdown suppresses non-small cell lung cancer cell tumor properties by the miR-545-3p/PDPK1 pathway
C Sun, H Guan, J Li, Y Gu - Open Medicine, 2023 - degruyter.com
Non-small cell lung cancer (NSCLC) accounts for 80% of total lung cancers, which are the
main killer of cancer-related death worldwide. Circular RNA (circRNA) has been found to …
main killer of cancer-related death worldwide. Circular RNA (circRNA) has been found to …
Exploring the impact of miR-128 in inflammatory diseases: A comprehensive study on autoimmune diseases
Abstract microRNAs (miRNAs) play a crucial role in various biological processes, including
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …
[HTML][HTML] Current landscape of miRNAs and TGF‐β signaling in lung cancer progression and therapeutic targets
BM Hussen, SJ Saleem, SR Abdullah… - Molecular and Cellular …, 2023 - Elsevier
Lung cancer (LC) is the primary reason for cancer-associated fatalities globally. Due to both
tumor-suppressing and tumor-promoting activities, the TGF-β family of growth factors is …
tumor-suppressing and tumor-promoting activities, the TGF-β family of growth factors is …
Slit2/Robo1 signaling inhibits small‐cell lung cancer by targeting β‐catenin signaling in tumor cells and macrophages
Small‐cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of lung cancer with
poor patient prognosis. However, the mechanisms that regulate SCLC progression and …
poor patient prognosis. However, the mechanisms that regulate SCLC progression and …
Chemoresistance Mechanisms in Non-Small Cell Lung Cancer—Opportunities for Drug Repurposing
R Kaur, PK Suresh - Applied Biochemistry and Biotechnology, 2023 - Springer
Globally, lung cancer contributes significantly to the public health burden–associated
mortality. As this form of cancer is insidious in nature, there is an inevitable diagnostic delay …
mortality. As this form of cancer is insidious in nature, there is an inevitable diagnostic delay …