Microenvironment‐based diabetic foot ulcer nanomedicine

F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …

Recent advances in responsive hydrogels for diabetic wound healing

S Zhang, G Ge, Y Qin, W Li, J Dong, J Mei, R Ma… - Materials Today Bio, 2023 - Elsevier
Poor wound healing after diabetes mellitus remains a challenging problem, and its
pathophysiological mechanisms have not yet been fully elucidated. Persistent bleeding …

[HTML][HTML] Wound microenvironment self-adaptive hydrogel with efficient angiogenesis for promoting diabetic wound healing

Z Shao, T Yin, J Jiang, Y He, T Xiang, S Zhou - Bioactive Materials, 2023 - Elsevier
Neovascularization is critical to improve the diabetic microenvironment, deliver abundant
nutrients to the wound and promote wound closure. However, the excess of oxidative stress …

[HTML][HTML] Photothermal antibacterial antioxidant conductive self-healing hydrogel with nitric oxide release accelerates diabetic wound healing

J He, Z Li, J Wang, T Li, J Chen, X Duan… - Composites Part B …, 2023 - Elsevier
Diabetic wound healing is affected by insufficient angiogenesis, oxidative damage, and
bacterial infection, resulting in a delayed healing process. There is an urgent need to design …

Scarless wound healing programmed by core-shell microneedles

Y Zhang, S Wang, Y Yang, S Zhao, J You… - Nature …, 2023 - nature.com
Effective reprogramming of chronic wound healing remains challenging due to the limited
drug delivery efficacy hindered by physiological barriers, as well as the inappropriate dosing …

Biomimetic Nanozyme-Decorated Hydrogels with H2O2-Activated Oxygenation for Modulating Immune Microenvironment in Diabetic Wound

Y Zhao, D Wang, T Qian, J Zhang, Z Li, Q Gong… - ACS …, 2023 - ACS Publications
Diabetic foot ulcers (DFUs) remain a devastating threat to human health. While hydrogels
are promising systems for DFU-based wound management, their effectiveness is often …

Bioinspired gradient structured soft actuators: From fabrication to application

H Liu, R Liu, K Chen, Y Liu, Y Zhao, X Cui… - Chemical Engineering …, 2023 - Elsevier
The gradient structure inherent in the biological system plays a key role in facilitating
efficient and precise actuation. To date, bioinspired gradient structured soft actuators have a …

Hydrogel wound dressings for diabetic foot ulcer treatment: status‐quo, challenges, and future perspectives

A Ko, C Liao - BMEMat, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU) are a common and often debilitating complication of diabetes that
can result in lower limb amputations if left untreated. Hydrogel dressings are three …

Chitosan and hyaluronic-based hydrogels could promote the infected wound healing

Q Bai, Q Gao, F Hu, C Zheng, W Chen, N Sun… - International Journal of …, 2023 - Elsevier
The most important function of skin is to prevent biological dehydration and protect internal
structures from the environment. When a wound becomes infected, the bacteria cause a …

Janus hydrogel with dual antibacterial and angiogenesis functions for enhanced diabetic wound healing

G Liu, Y Zhou, Z Xu, Z Bao, L Zheng, J Wu - Chinese Chemical Letters, 2023 - Elsevier
Anti-infection and neovascularization at the wound site are two vital factors that accelerate
diabetic wound healing. However, for a wound healing dressing, the two functions need to …