[HTML][HTML] Modeling Methamphetamine Use Disorder and Relapse in Animals: Short-and Long-term Epigenetic, Transcriptional., and Biochemical Consequences in the …
K Elhadi, AP Daiwile, JL Cadet - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Methamphetamine use disorder (MUD) is a neuropsychiatric disorder characterized by
binge drug taking episodes, intervals of abstinence, and relapses to drug use even during …
binge drug taking episodes, intervals of abstinence, and relapses to drug use even during …
[HTML][HTML] Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study
EJE Engeli, AG Russo, S Ponticorvo, N Zoelch… - NeuroImage: Clinical, 2023 - Elsevier
Craving is a core symptom of cocaine use disorder and a major factor for relapse risk. To
date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine …
date, there is no pharmacological therapy to treat this disease or at least to alleviate cocaine …
ADX106772, an mGlu2 receptor positive allosteric modulator, selectively attenuates oxycodone taking and seeking
JM Illenberger, FJ Flores-Ramirez, A Matzeu… - …, 2023 - Elsevier
Opioid abuse and overdose have risen to epidemic proportions in the United States.
Oxycodone is the most abused prescription opioid. Treatments for opioid use disorder …
Oxycodone is the most abused prescription opioid. Treatments for opioid use disorder …
[HTML][HTML] Role of deep brain stimulation (DBS) in addiction disorders
J Iqbal, MNM Mansour, HA Saboor… - Surgical Neurology …, 2023 - ncbi.nlm.nih.gov
Background: Addiction disorders pose significant challenges to public health, necessitating
innovative treatments. This assesses deep brain stimulation (DBS) as a potential …
innovative treatments. This assesses deep brain stimulation (DBS) as a potential …
The mGlu2/3 agonist LY379268 reduces sucrose taking, seeking, and motivation in male and female rats
JW Grimm, F Sauter, D MacDougall… - Behavioural …, 2023 - journals.lww.com
Objectives The mGlu2/3 receptor agonist LY379268 reduces sucrose-seeking, but not
sucrose-taking, in male rats. This study explored the generality of this effect across the …
sucrose-taking, in male rats. This study explored the generality of this effect across the …
The neurobiology of exercise and drug-seeking behavior
Epidemiological studies consistently report that physical activity is inversely related to
substance use and abuse. The mesolimbic reward pathway, which includes dopaminergic …
substance use and abuse. The mesolimbic reward pathway, which includes dopaminergic …