Chitosan: a potential biopolymer in drug delivery and biomedical applications
Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has
surfaced as a material of promise for drug delivery and biomedical applications. Different …
surfaced as a material of promise for drug delivery and biomedical applications. Different …
The mucin family of proteins: candidates as potential biomarkers for colon cancer
Simple Summary Colorectal cancer is the second leading cause of cancer-related deaths in
the United States with an overall 5-year survival of 65%. While there have been many …
the United States with an overall 5-year survival of 65%. While there have been many …
Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies
Aberrantly expressed onco-mucin 16 (MUC16) and its post-cleavage generated surface
tethered carboxy-terminal (MUC16-Cter) domain are strongly associated with poor …
tethered carboxy-terminal (MUC16-Cter) domain are strongly associated with poor …
Molecular classification of appendiceal adenocarcinoma
PURPOSE Appendiceal adenocarcinomas (ACs) are rare, histologically diverse
malignancies treated as colorectal cancers despite having distinct biology and clinical …
malignancies treated as colorectal cancers despite having distinct biology and clinical …
Mucins as potential biomarkers for early detection of cancer
Simple Summary Early cancer detection is a challenge in treating cancer patients.
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …
Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis
Abstract Mucin4 (MUC4) appears early during pancreatic intraepithelial neoplasia-1
(PanIN1), coinciding with the expression of epidermal growth factor receptor-1 (EGFR). The …
(PanIN1), coinciding with the expression of epidermal growth factor receptor-1 (EGFR). The …
The expression of O-linked glycosyltransferase GALNT7 in breast cancer is dependent on estrogen-, progesterone-, and HER2-receptor status, with prognostic …
GALNT7 is a glycosyltransferase enzyme transferring N-acetylgalactosamine to initiate O-
linked glycosylation in the Golgi apparatus. Breast cancer is the most common cancer in …
linked glycosylation in the Golgi apparatus. Breast cancer is the most common cancer in …
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer
KM Muilenburg, CC Isder, P Radhakrishnan, SK Batra… - Cancer letters, 2023 - Elsevier
Pancreatic cancer is difficult to resect due to its unique challenges, often leading to
incomplete tumor resections. Fluorescence-guided surgery (FGS), also known as …
incomplete tumor resections. Fluorescence-guided surgery (FGS), also known as …
Molecular research in pancreatic cancer: Small molecule inhibitors, their mechanistic pathways and beyond
Pancreatic enzymes assist metabolic digestion, and hormones like insulin and glucagon
play a critical role in maintaining our blood sugar levels. A malignant pancreas is incapable …
play a critical role in maintaining our blood sugar levels. A malignant pancreas is incapable …
Clinical and molecular attributes and evaluation of pancreatic cystic neoplasm
P Raut, RK Nimmakayala, SK Batra… - Biochimica et Biophysica …, 2023 - Elsevier
Intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs)
are all considered “Pancreatic cystic neoplasms (PCNs)” and show a varying risk of …
are all considered “Pancreatic cystic neoplasms (PCNs)” and show a varying risk of …