Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Endotheliopathy in acute COVID-19 and long COVID
AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …
functions under physiological and pathological conditions. Since endothelial dysfunction …
COVID-19 and Long COVID: disruption of the neurovascular unit, blood-brain barrier, and tight junctions
D Kempuraj, KK Aenlle, J Cohen… - The …, 2023 - journals.sagepub.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …
Cell-specific mechanisms in the heart of COVID-19 patients
From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …
abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis …
Lipid nanoparticles for nucleic acid delivery to endothelial cells
GW Liu, EB Guzman, N Menon, RS Langer - Pharmaceutical Research, 2023 - Springer
Endothelial cells play critical roles in circulatory homeostasis and are also the gateway to
the major organs of the body. Dysfunction, injury, and gene expression profiles of these cells …
the major organs of the body. Dysfunction, injury, and gene expression profiles of these cells …
The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
Status of major hemostatic components in the setting of COVID-19: the effect on endothelium, platelets, coagulation factors, fibrinolytic system, and complement
The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …
Variation in presepsin and thrombomodulin levels for predicting COVID-19 mortality
A Yamazaki, Y Nukui, T Kameda, R Saito, Y Koda… - Scientific Reports, 2023 - nature.com
Abstract Coronavirus disease (COVID-19) has caused extensive mortality globally;
therefore, biomarkers predicting the severity and prognosis of COVID-19 are essential. This …
therefore, biomarkers predicting the severity and prognosis of COVID-19 are essential. This …
Platelet-neutrophil interaction in COVID-19 and vaccine-induced thrombotic thrombocytopenia
Coronavirus disease 2019 (COVID-19) is known to commonly induce a thrombotic diathesis,
particularly in severely affected individuals. So far, this COVID-19-associated coagulopathy …
particularly in severely affected individuals. So far, this COVID-19-associated coagulopathy …
Extracellular vesicles of COVID-19 patients reflect inflammation, thrombogenicity, and disease severity
A Aharon, A Dangot, F Kinaani, M Zavaro… - International Journal of …, 2023 - mdpi.com
Severe COVID-19 infections present with cytokine storms, hypercoagulation, and acute
respiratory distress syndrome, with extracellular vesicles (EVs) being involved in …
respiratory distress syndrome, with extracellular vesicles (EVs) being involved in …