Epigenetics in cancer development, diagnosis and therapy
Cancer is a dangerous disease and one of the leading causes of death in the world. In 2020,
there were nearly 10 million cancer deaths and approximately 20 million new cases. New …
there were nearly 10 million cancer deaths and approximately 20 million new cases. New …
[HTML][HTML] Recent advances in understanding DNA methylation of prostate cancer
HJ Shin, JT Hua, H Li - Frontiers in Oncology, 2023 - frontiersin.org
Epigenetic modifications, such as DNA methylation, is widely studied in cancer. DNA
methylation patterns have been shown to distinguish between benign and malignant tumors …
methylation patterns have been shown to distinguish between benign and malignant tumors …
[HTML][HTML] Aberrant DNA Methylation, Expression, and Occurrence of Transcript Variants of the ABC Transporter ABCA7 in Breast Cancer
K Zappe, A Kopic, A Scheichel, AK Schier, LE Schmidt… - Cells, 2023 - mdpi.com
The ABC transporter ABCA7 has been found to be aberrantly expressed in a variety of
cancer types, including breast cancer. We searched for specific epigenetic and genetic …
cancer types, including breast cancer. We searched for specific epigenetic and genetic …
[HTML][HTML] meth-SemiCancer: a cancer subtype classification framework via semi-supervised learning utilizing DNA methylation profiles
JM Choi, C Park, H Chae - BMC bioinformatics, 2023 - Springer
Background Identification of the cancer subtype plays a crucial role to provide an accurate
diagnosis and proper treatment to improve the clinical outcomes of patients. Recent studies …
diagnosis and proper treatment to improve the clinical outcomes of patients. Recent studies …
Novel insights into DNA methylation-based epigenetic regulation of breast tumor angiogenesis
SM Bhat, PR Prasad, MB Joshi - … Review of Cell and Molecular Biology, 2023 - Elsevier
Breast tumors are highly vascularized and dependent on angiogenesis for growth,
progression and metastasis. Like other solid tumors, vasculature in breast tumors also …
progression and metastasis. Like other solid tumors, vasculature in breast tumors also …
Peripheral blood DNA methylation analysis reveals epigenetic marks associated with hereditary breast and ovarian cancer risk
FV Paniagua, MR de la Cruz, HM Gregorio… - 2023 - researchsquare.com
Background. Only a fraction of 15-20% of hereditary breast and ovarian cancer (HBOC)
patients carry pathogenic coding genetic variants. Therefore, other pathogenic molecular …
patients carry pathogenic coding genetic variants. Therefore, other pathogenic molecular …
Differentially Methylated Region Analysis and Application on Integrative Analysis of Multi-Omics Data
Q Fu - 2023 - search.proquest.com
DNA methylation is one of the most well-known and well-studied epigenetic mechanisms
that influences gene expression. Micro-RNA expression is also identified as playing a critical …
that influences gene expression. Micro-RNA expression is also identified as playing a critical …