Therapeutic effects and the impact of statins in the prevention of ulcerative colitis in preclinical models: A systematic review

KD Vital, BG Cardoso, IP Lima… - Fundamental & …, 2023 - Wiley Online Library
Ulcerative Colitis (UC) is a chronic inflammatory condition of the large intestines. Although
great advances have been made in the management of the disease with the introduction of …

The effect of lipid-lowering therapies on the pro-inflammatory and anti-inflammatory properties of vascular endothelial cells

E Woźniak, M Broncel, M Niedzielski, A Woźniak… - Plos one, 2023 - journals.plos.org
Atherosclerosis and cardiovascular events can be prevented, or treated, using statin
therapy, either alone or in combination with ezetimibe. Chronic inflammation, vascular …

Atorvastatin improves intestinal mucositis induced by 5-fluorouracil in mice by modulating the and epithelial barrier and inflammatory signaling pathways

KD Vital, LO Pires, B Gallotti, JL Silva, LCL Jesus… - 2023 - researchsquare.com
Chemotherapy-induced intestinal mucositis is a major side effect of cancer treatment. Statins
are 3-hydroxy-3-methyl glutaryl coenzyme reductase inhibitors used to treat …