MRI biomarkers for memory-related impairment in amyotrophic lateral sclerosis: a systematic review

S Ghaderi, F Fatehi, S Kalra… - … Lateral Sclerosis and …, 2023 - Taylor & Francis
Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …

[HTML][HTML] Mesenchymal stem cell therapy in amyotrophic lateral sclerosis (ALS) patients: A comprehensive review of disease information and future perspectives

S Najafi, P Najafi, NK Farkhad, GH Torshizi… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a rare deadly progressive neurological disease that
primarily affects the upper and lower motor neurons with an annual incidence rate of 0.6 to …

Development of abnormalities at the neuromuscular junction in the SOD1-G93A mouse model of ALS: dysfunction then disruption of postsynaptic structure precede …

J McIntosh, I Mekrouda, M Dashti… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction The ultimate deficit in amyotrophic lateral sclerosis (ALS) is neuromuscular
junction (NMJ) loss, producing permanent paralysis, ultimately in respiratory muscles …

Comparison of spinal magnetic resonance imaging and classical clinical factors in predicting motor capacity in amyotrophic lateral sclerosis

M Khamaysa, M Lefort, M Pélégrini-Issac… - Journal of …, 2023 - Springer
Background Motor capacity is crucial in amyotrophic lateral sclerosis (ALS) clinical trial
design and patient care. However, few studies have explored the potential of multimodal …

[HTML][HTML] Potential Applications for Growth Hormone Secretagogues Treatment of Amyotrophic Lateral Sclerosis

R Meanti, E Bresciani, L Rizzi, S Coco… - Current …, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) arises from neuronal death due to complex interactions
of genetic, molecular, and environmental factors. Currently, only two drugs, riluzole and …

Targeting mitochondrial dysfunction to salvage cellular senescence for managing neurodegeneration

K Sharma, J Sarkar, A Trisal, R Ghosh, A Dixit… - Advances in Protein …, 2023 - Elsevier
Aging is an inevitable phenomenon that causes a decline in bodily functions over time. One
of the most important processes that play a role in aging is senescence. Senescence is …

Biosensors for Salivary Biomarker Detection of Cancer and Neurodegenerative Diseases

B Sajeevan, MG Gopika, Sreelekshmi… - Biosensors …, 2023 - Wiley Online Library
Biosensors are devices that make use of biorecognition elements and produce measurable
signals proportional to the concentration of the target biomolecules for the prognosis and …

Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis-An integrated bioinformatics …

A Datta, M D'costa, A Bothe, H Zayed - Advances in Protein …, 2023 - europepmc.org
The mechanisms responsible for the pathogenesis and progression of Amyotrophic Lateral
Sclerosis (ALS) remain poorly understood, making the diagnosis of ALS challenging. We …

Role of Biomarkers in Pathogenesis and Updated Treatment of Motor Neuron Disease: A Review Article

R Kumar, A Kumar, VK Bharti… - Mathews Journal …, 2023 - mathewsopenaccess.com
One of the most severe adult-onset neurodegenerative illnesses is motor neuron disease
(MND), which most frequently manifests as amyotrophic lateral sclerosis (ALS). Significant …

[图书][B] Bioinformatic Strategies for Population Precision Health

C Caggiano - 2023 - search.proquest.com
Population precision health represents a paradigm shift in healthcare, emphasizing the
need for tailored and personalized approaches to improve health outcomes at a population …