Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …

Bipolar disorder (BD) profoundly affects cognitive and psychosocial functioning, leading to a
significant illness burden on patients and their families. Genetic factors are predominant in …

Background The neural underpinnings of bipolar disorder (BD) remain poorly understood.
The cerebellum is ideally positioned to modulate emotional regulation circuitry yet has been …

Multiple forms of parental psychopathology have been associated with differences in
subcortical brain volume. However, few studies have considered the role of comorbidity …

Schizophrenia (SCZ) and bipolar disorder (BD) are severe psychiatric disorders that share
clinical features and several risk genes. Important information about their genetic …

Compromised white matter has been reported in schizophrenia; however, few studies have
investigated neurochemical abnormalities underlying microstructural differences. N …

Abstract Background and Hypothesis Endophenotypes can help to bridge the gap between
psychosis and its genetic predispositions, but their underlying mechanisms remain largely …

Although attention-deficit/hyperactivity disorder (ADHD) and a family history of bipolar I
disorder (BD) are associated with increased risk for developing BD, their neuroanatomical …

Patients with bipolar disorder (BD) and their first-degree relatives exhibit alterations in brain
volume and cortical structure, whereas the underlying genetic mechanisms remain unclear …

Background Emerging evidence points towards the involvement of the cerebellum in the
processing of emotions and pathophysiology of mood disorders. However, cerebellar and …