[HTML][HTML] Do interleukin-1 and interleukin-6 antagonists hold any place in the treatment of atherosclerotic cardiovascular disease and related co-morbidities? an …

A Dimosiari, D Patoulias, GD Kitas… - Journal of Clinical …, 2023 - mdpi.com
Cardiovascular disease (CVD) constitutes a real pandemic of the 21st century. According to
data from the Centers for Disease Control and Prevention, one person dies every 34 min …

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets

M Li, M Wang, Y Wen, H Zhang, GN Zhao, Q Gao - MedComm, 2023 - Wiley Online Library
Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

[HTML][HTML] Target and cell therapy for atherosclerosis and CVD

YV Markina, TV Kirichenko, TV Tolstik… - International Journal of …, 2023 - mdpi.com
Cardiovascular diseases (CVD) and, in particular, atherosclerosis, remain the main cause of
death in the world today. Unfortunately, in most cases, CVD therapy begins after the onset of …

[HTML][HTML] Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating …

L Ji, T Song, C Ge, Q Wu, L Ma, X Chen, T Chen… - Biomedicine & …, 2023 - Elsevier
Objective This study aims at investigating the potential targets and functional mechanisms of
Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network …

Association between coronary artery calcium and thoracic spine bone mineral density: Multiethnic Study of Atherosclerosis (MESA)

VS Manubolu, S Mao, A Kinninger, S Dahal… - Nutrition, Metabolism …, 2023 - Elsevier
Background and aims Previously, osteoporosis and coronary artery disease were
considered unrelated. However, beyond age, these two conditions appear to share common …

[HTML][HTML] Dyslipidemia is associated with inflammation and organ involvement in systemic lupus erythematosus

S Huang, Z Zhang, Y Cui, G Yao, X Ma, H Zhang - Clinical Rheumatology, 2023 - Springer
Introduction Disturbed lipid metabolism was observed in systemic lupus erythematosus
(SLE) patients. This study aimed to evaluate the relationships between dyslipidemia and …

Novel soybean polypeptide dglycin alleviates atherosclerosis in apolipoprotein E-deficient mice

H Zhao, P Dan, J Xi, Z Chen, P Zhang, W Wei… - International Journal of …, 2023 - Elsevier
Atherosclerosis is a dominant cause of cardiovascular disease. Accumulation of low-density
lipoproteins (LDL), formation of foam cells, and endothelial dysfunction within the arterial …

Pro‐inflammatory cytokines mediating senescence of vascular endothelial cells in atherosclerosis

D Shang, H Liu, Z Tu - Fundamental & Clinical Pharmacology, 2023 - Wiley Online Library
Atherosclerosis (AS) is a chronic inflammatory vascular disease, and aging is a major risk
factor. The accumulation of senescent vascular endothelial cells (VECs) often leads to …

The effect of omega-3 polyunsaturated fatty acid intake on blood levels of omega-3s in people with chronic atherosclerotic disease: a systematic review

NC Nayda, JM Thomas, CL Delaney… - Nutrition …, 2023 - academic.oup.com
Context Atherosclerosis is a systemic pro-inflammatory and pro-oxidative disease,
accounting for approximately a third of deaths globally. It has been proposed that omega-3s …

[HTML][HTML] Leukocytes carrying Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutations invade Human Atherosclerotic Plaques

M von Scheidt, S Bauer, A Ma, K Hao, T Kessler… - medRxiv, 2023 - ncbi.nlm.nih.gov
Background: Leukocyte progenitors derived from clonal hematopoiesis of undetermined
potential (CHIP) are associated with increased cardiovascular events. However, the …