Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections

RK Shields, DL Paterson… - Clinical Infectious …, 2023 - academic.oup.com
Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRAB) is one of
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …

Guidelines for the diagnosis, treatment, prevention and control of infections caused by carbapenem-resistant gram-negative bacilli

M Zeng, J Xia, Z Zong, Y Shi, Y Ni, F Hu, Y Chen… - Journal of Microbiology …, 2023 - Elsevier
The dissemination of carbapenem-resistant Gram-negative bacilli (CRGNB) is a global
public health issue. CRGNB isolates are usually extensively drug-resistant or pandrug …

Cefiderocol-Based versus Colistin-Based Regimens for Severe Carbapenem-Resistant Acinetobacter baumannii Infections: A Propensity Score-Weighted …

M Mazzitelli, D Gregori, L Sasset, M Trevenzoli… - Microorganisms, 2023 - mdpi.com
Background. A large increase in multi-drug-resistant Acinetobacter baumannii, especially
carbapenem-resistant strains, occurred during the first two years of the COVID-19 pandemic …

Polymyxin combination therapy for multidrug-resistant, extensively-drug resistant, and difficult-to-treat drug-resistant gram-negative infections: is it superior to …

A Ardebili, A Izanloo, M Rastegar - Expert Review of Anti-infective …, 2023 - Taylor & Francis
Introduction The increasing prevalence of infections with multidrug-resistant (MDR),
extensively-drug resistant (XDR) or difficult-to-treat drug resistant (DTR) Gram-negative …

Aminoglycosides for the treatment of severe infection due to resistant gram-negative pathogens

M Thy, JF Timsit, E de Montmollin - Antibiotics, 2023 - mdpi.com
Aminoglycosides are a family of rapidly bactericidal antibiotics that often remain active
against resistant Gram-negative bacterial infections. Over the past decade, their use in …

In Vitro Synergistic Activity of Antimicrobial Combinations against Carbapenem- and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae

P Mantzana, E Protonotariou, A Kassomenaki… - Antibiotics, 2023 - mdpi.com
Polymyxins are commonly used as the last resort for the treatment of MDR Acinetobacter
baumannii and Klebsiella pneumoniae nosocomial infections; however, apart from the …

Effectiveness of First-Line Therapy with Old and Novel Antibiotics in Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant Acinetobacter baumannii: A …

L Dalfino, M Stufano, DF Bavaro, L Diella, A Belati… - Antibiotics, 2023 - mdpi.com
Evidence-based, standard antibiotic therapy for ventilator-associated pneumonia (VAP)
caused by carbapenem-resistant Acinetobacter baumannii (CRAB) is a relevant unmet …

Efficacy of Cefoperazone Sulbactam in Patients with Acinetobacter Infections: A Systematic Review of the Literature

GS Kogilathota Jagirdhar, K Rama, ST Reddy… - Antibiotics, 2023 - mdpi.com
Introduction: Acinetobacter baumannii (AB) is a multidrug-resistant pathogen commonly
associated with nosocomial infections. The resistance profile and ability to produce biofilm …

[HTML][HTML] Physiologically-based pharmacokinetic modeling to inform dosing regimens and routes of administration of rifampicin and colistin combination against …

J Zhang, C Song, M Wu, J Yue, S Zhu, P Zhu… - European Journal of …, 2023 - Elsevier
Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) is resistant to
major antibiotics such as penicillin, cephalosporin, fluoroquinolone and aminoglycoside …

Current State of Antimicrobial Treatment of Lower Respiratory Tract Infections Due to Carbapenem-Resistant Acinetobacter baumannii

M Merli, F D'Amico, G Travi, M Puoti - Future Pharmacology, 2023 - mdpi.com
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a worldwide non-fermenting
Gram-negative bacillus responsible for potentially severe nosocomial infections, especially …