Spt6 directly interacts with Cdc73 and is required for Paf1 complex occupancy at active genes in Saccharomyces cerevisiae
MA Ellison, S Namjilsuren, MK Shirra… - Nucleic Acids …, 2023 - academic.oup.com
Abstract The Paf1 complex (Paf1C) is a conserved transcription elongation factor that
regulates transcription elongation efficiency, facilitates co-transcriptional histone …
regulates transcription elongation efficiency, facilitates co-transcriptional histone …
Paf1 complex subunit Rtf1 stimulates H2B ubiquitylation by interacting with the highly conserved N-terminal helix of Rad6
T Fetian, BM McShane, NL Horan… - Proceedings of the …, 2023 - National Acad Sciences
Histone modifications coupled to transcription elongation play important roles in regulating
the accuracy and efficiency of gene expression. The monoubiquitylation of a conserved …
the accuracy and efficiency of gene expression. The monoubiquitylation of a conserved …
Rtf1 Transcriptionally Regulates Neonatal and Adult Cardiomyocyte Biology
AD Langenbacher, F Lu, L Crisman… - Journal of …, 2023 - mdpi.com
The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription
regulatory protein that promotes transcription elongation and the co-transcriptional …
regulatory protein that promotes transcription elongation and the co-transcriptional …
[HTML][HTML] Rtf1-dependent transcriptional pausing regulates cardiogenesis
AD Langenbacher, F Lu, L Tsang, ZYS Huang, B Keer… - bioRxiv, 2023 - ncbi.nlm.nih.gov
During heart development, a well-characterized network of transcription factors initiates
cardiac gene expression and defines the precise timing and location of cardiac progenitor …
cardiac gene expression and defines the precise timing and location of cardiac progenitor …
Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms
S MacKinnon, V Pagé, JJ Chen, A Shariat-Panahi… - PLoS …, 2023 - journals.plos.org
Heterochromatin is a condensed chromatin structure that represses transcription of repetitive
DNA elements and developmental genes, and is required for genome stability …
DNA elements and developmental genes, and is required for genome stability …