Pathogenesis of Zika virus infection

MI Giraldo, M Gonzalez-Orozco… - Annual Review of …, 2023 - annualreviews.org
Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Interaction of the pre-and postnatal environment in the maternal immune activation model

A Gundacker, L Cuenca Rico, P Stoehrmann… - Discover mental …, 2023 - Springer
Adverse influences during pregnancy are associated with a range of unfavorable outcomes
for the developing offspring. Maternal psychosocial stress, exposure to infections and …

Favipiravir Suppresses Zika Virus (ZIKV) through Activity as a Mutagen

EJ Franco, E Cella, X Tao, KC Hanrahan, T Azarian… - Microorganisms, 2023 - mdpi.com
In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV)
suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC …

Mice as an animal model for Japanese encephalitis virus research: mouse susceptibility, infection route, and viral pathogenesis

JC Frank, BH Song, YM Lee - Pathogens, 2023 - mdpi.com
Japanese encephalitis virus (JEV), a zoonotic flavivirus, is principally transmitted by
hematophagous mosquitoes, continually between susceptible animals and incidentally from …

ZIKV induction of tristetraprolin in endothelial and Sertoli cells post-transcriptionally inhibits IFNβ/λ expression and promotes ZIKV persistence

WR Schutt, JN Conde, MC Mladinich, GE Himmler… - Mbio, 2023 - Am Soc Microbiol
Zika virus (ZIKV) is a mosquito-borne Flavivirus that persistently infects patients; enters
protected brain, placental, and testicular compartments; is sexually transmitted; and causes …

Pathophysiology and mechanisms of hearing impairment related to neonatal infection diseases

D Capra, MF DosSantos, CK Sanz… - Frontiers in …, 2023 - frontiersin.org
The inner ear, the organ of equilibrium and hearing, has an extraordinarily complex and
intricate arrangement. It contains highly specialized structures meticulously tailored to permit …

Roles of TGF-β1 in Viral Infection during Pregnancy: Research Update and Perspectives

QD Trinh, NTK Pham, K Takada, H Ushijima… - International Journal of …, 2023 - mdpi.com
Transforming growth factor-beta 1 (TGF-β1) is a pleiotropic growth factor playing various
roles in the human body including cell growth and development. More functions of TGF-β1 …

A Pocket Guide to CCR5—Neurotropic Flavivirus Edition

A Garg, JK Lim - Viruses, 2023 - mdpi.com
CCR5 is among the most studied chemokine receptors due to its profound significance in
human health and disease. The notion that CCR5 is a functionally redundant receptor was …

Clinical and Acoustic Alterations of Swallowing in Children Exposed to Zika Virus during Pregnancy in a Cohort in Amazonas, Brazil: A Case Series Study

CS Rodrigues, RKS Souza, CV Rocha Neto, RH Otani… - Viruses, 2023 - mdpi.com
Oropharyngeal dysphagia (OD) is a swallowing disorder that involves difficulty in safely
passing the food bolus from the oral cavity to the stomach. OD is a common problem in …

Developing brain under renewed attack: viral infection during pregnancy

H Recaioglu, SM Kolk - Frontiers in Neuroscience, 2023 - frontiersin.org
Living in a globalized world, viral infections such as CHIKV, SARS-COV-2, and ZIKV have
become inevitable to also infect the most vulnerable groups in our society. That poses a …