Manipulating the destiny of wild populations using CRISPR

R Raban, JM Marshall, BA Hay… - Annual review of …, 2023 - annualreviews.org
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …

Incorporating ecology into gene drive modelling

J Kim, KD Harris, IK Kim, S Shemesh… - Ecology …, 2023 - Wiley Online Library
Gene drive technology, in which fast‐spreading engineered drive alleles are introduced into
wild populations, represents a promising new tool in the fight against vector‐borne diseases …

[HTML][HTML] Review of gene drive modelling and implications for risk assessment of gene drive organisms

JL Frieß, CR Lalyer, B Giese, S Simon, M Otto - Ecological Modelling, 2023 - Elsevier
Synthetic gene drive (GD) systems constitute a form of novel invasive environmental
biotechnology with far-reaching consequences beyond those of other known genetically …

Leveraging eco-evolutionary models for gene drive risk assessment

MA Combs, AJ Golnar, JM Overcash, AL Lloyd… - Trends in Genetics, 2023 - cell.com
Engineered gene drives create potential for both widespread benefits and irreversible harms
to ecosystems. CRISPR-based systems of allelic conversion have rapidly accelerated gene …

Modeling priorities as gene drive mosquito projects transition from lab to field

JM Marshall, AR North - Mosquito gene drives and the malaria …, 2023 - taylorfrancis.com
This chapter discusses the modeling priorities as gene drive mosquito projects advance
from the lab to the field. Mathematical modeling has a central role to play in determining the …

透過全基因組核酸多態型資料研究台灣南部埃及斑蚊在小尺度的族群結構

曾奕承 - 2023 - tdr.lib.ntu.edu.tw
埃及斑蚊(Aedes aegypti) 是登革熱(Dengue fever) 等蚊媒傳染病(Mosquito-Borne Diseases)
主要傳播的媒介. 瞭解埃及斑蚊的分布及散播有益於控制病媒蚊的散播. 本研究採集了台南市 …

Mathematical models of gene drive for population management

L Klay - 2023 - theses.hal.science
Artificial gene drive is a genetic engineering technology that could be used for the control of
natural populations. Gene drive alleles bias their own transmission and can therefore …