An update of epigenetic drugs for the treatment of cancers and brain diseases: a comprehensive review
Z Sahafnejad, S Ramazi, A Allahverdi - Genes, 2023 - mdpi.com
Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …
investigation of any alteration in gene expression patterns that is not attributed to changes in …
Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential
M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
aaUrgent Needs of Caregiving in Ageing Populations with Alzheimer's Disease and Other Chronic Conditions: Support Our Loved Ones
The ageing process begins at birth. It is a life-long process, and its exact origins are still
unknown. Several hypotheses attempt to describe the normal ageing process, including …
unknown. Several hypotheses attempt to describe the normal ageing process, including …
Histone modifications in Alzheimer's disease
DA Santana, MAC Smith, ES Chen - Genes, 2023 - mdpi.com
Since Late-onset Alzheimer's disease (LOAD) derives from a combination of genetic variants
and environmental factors, epigenetic modifications have been predicted to play a role in the …
and environmental factors, epigenetic modifications have been predicted to play a role in the …
Targeting the molecular & cellular pillars of human aging with exercise
Biological aging is the main driver of age‐associated chronic diseases. In 2014, the United
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
Genomic instability and epigenetic changes during aging
L López-Gil, A Pascual-Ahuir, M Proft - International Journal of Molecular …, 2023 - mdpi.com
Aging is considered the deterioration of physiological functions along with an increased
mortality rate. This scientific review focuses on the central importance of genomic instability …
mortality rate. This scientific review focuses on the central importance of genomic instability …
A socioecological-genetic framework of culture and personality: Their roots, trends, and interplay
JG Lu, V Benet-Martínez… - Annual Review of …, 2023 - annualreviews.org
Culture and personality are two central topics in psychology. Individuals are culturally
influenced influencers of culture, yet the research linking culture and personality has been …
influenced influencers of culture, yet the research linking culture and personality has been …
[HTML][HTML] Epigenetic modification impacting brain functions: Effects of physical activity, micronutrients, caffeine, toxins, and addictive substances
R Mallick, AK Duttaroy - Neurochemistry International, 2023 - Elsevier
Abstract Changes in gene expression are involved in many brain functions. Epigenetic
processes modulate gene expression by histone modification and DNA methylation or RNA …
processes modulate gene expression by histone modification and DNA methylation or RNA …
Methylation-based biological age and hypertension prevalence and incidence
Background: Hypertension is common in older individuals and is a major risk factor for
cardiovascular disease. Blood DNA methylation profiles have been used to derive metrics of …
cardiovascular disease. Blood DNA methylation profiles have been used to derive metrics of …