The design of bioisosteres represents a creative and productive approach to improve a
molecule, including by enhancing potency, addressing pharmacokinetic challenges …

The peach–potato aphid, Myzus persicae (Sulzer), is one of the most important pests of
economic crops. It damages the plant directly by consuming nutrients and water and …

A pilot study among farming households in eastern Iowa was conducted to assess human
exposure to neonicotinoids (NEOs). The study was in a region with intense crop and …

Neonicotinoids and neonicotinoid-like compounds (NNIs) are frequently used insecticides
worldwide and exposure scenarios can vary widely between countries and continents. We …

Current-use pesticides are ubiquitous in freshwaters globally, often at very low
concentrations. Emerging aquatic insects can accumulate pesticides during their aquatic …

The worldwide decline in pollinating insects is alarming. One of the main anthropogenic
drivers is the massive use of pesticides in agriculture. Risk assessment procedures test …

The potential toxicity of flupyradifurone (FPF) to honey bees has been a subject of
controversy in recent years. Understanding the effect of pesticides on nurse bees is …

Novel pesticides broflanilide (BFI), afidopyropen (ADP), and flupyradifurone (FPO) have
been widely used and become the new organic pollutants. However, uptake, translocation …

Novel agrochemicals have been successfully developed using target-based drug design
(TBDD). To discover a novel, efficient, and highly selective nicotinic insecticide candidate …

In our work we study the toxic effects of the prepared pyridine and pyradazine derivatives.
Five compounds have been synthesized in pure state as reported procedures, and their …