The American Diabetes Association (ADA)“Standards of Care in Diabetes” includes the
ADA's current clinical practice recommendations and is intended to provide the components …

Arterial hypertension is a leading cause of death globally. Due to ageing, the rising
incidence of obesity, and socioeconomic and environmental changes, its incidence …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Background Aldosterone synthase controls the synthesis of aldosterone and has been a
pharmacologic target for the treatment of hypertension for several decades. Selective …

Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …

Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

ABSTRACT Background Mineralocorticoid receptor antagonists (MRAs) reduce systolic
blood pressure (SBP) and increase serum potassium concentration ([K+]). This indirect …

Baxdrostat is a selective inhibitor of aldosterone synthase designed for the treatment of
disorders associated with elevated aldosterone. This study evaluated the safety …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …