Collab or Cancel? Bacterial Influencers of Inflammasome Signaling

BI Herrmann, JP Grayczyk… - Annual Review of …, 2023 - annualreviews.org
The immune system of multicellular organisms protects them from harmful microbes. To
establish an infection in the face of host immune responses, pathogens must evolve specific …

Overview of Yersinia pestis Metallophores: Yersiniabactin and Yersinopine

T Chaaban, Y Mohsen, Z Ezzeddine, G Ghssein - Biology, 2023 - mdpi.com
Simple Summary Although there was a significant decrease in morbidity and mortality due to
plague-related infections throughout the 20th century, these have not been eradicated. The …

[HTML][HTML] Yersinia pestis and Plague: Some knowns and unknowns

R Yang, S Atkinson, Z Chen, Y Cui, Z Du… - Zoonoses (Burlington …, 2023 - ncbi.nlm.nih.gov
Since its first identification in 1894 during the third pandemic in Hong Kong, there has been
significant progress of understanding the lifestyle of Yersinia pestis, the pathogen that is …

[HTML][HTML] Arcobacteraceae comparative genome analysis demonstrates genome heterogeneity and reduction in species isolated from animals and associated with …

D Buzzanca, PJ Kerkhof, V Alessandria, K Rantsiou… - Heliyon, 2023 - cell.com
Abstract The Arcobacteraceae family groups Gram-negative bacterial species previously
included in the family Campylobacteraceae. These species of which some are considered …

Peptide MSI‐1 inhibited MCR‐1 and regulated outer membrane vesicles to combat immune evasion of Escherichia coli

X Ye, J Wang, P Xu, X Yang, Q Shi, G Liu… - Microbial …, 2023 - Wiley Online Library
Polymyxin resistance is conferred by MCR‐1 (mobile colistin resistance 1)‐induced
lipopolysaccharide (LPS) modification of G− bacteria. However, the peptide MSI‐1 exerts …

Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells

J Zhang, IE Brodsky, S Shin - Mbio, 2023 - Am Soc Microbiol
Yersinia are Gram-negative zoonotic bacteria that use a type III secretion system (T3SS) to
inject Yersinia outer proteins into the host cytosol to subvert essential components of innate …

Applied genomics for identification of virulent biothreats and for disease outbreak surveillance

MC Nwadiugwu, N Monteiro - Postgraduate medical journal, 2023 - academic.oup.com
Fortifying our preparedness to cope with biological threats by identifying and targeting
virulence factors may be a preventative strategy for curtailing infectious disease outbreak …

Yersinia Type III-Secreted Effectors Subvert Caspase-4-dependent Inflammasome Activation in Human Cells

J Zhang, IE Brodsky, S Shin - bioRxiv, 2023 - biorxiv.org
Yersinia are gram-negative zoonotic bacteria that use a type three secretion system (T3SS)
to inject Yersinia outer proteins (Yops) into the host cytosol in order to subvert essential …

Yersinia pestis Δail Mutants Are Not Susceptible to Human Complement Bactericidal Activity in the Flea

AM Kolodziejek, SW Bearden, S Maes… - Applied and …, 2023 - Am Soc Microbiol
Ail confers serum resistance in humans and is a critical virulence factor of Y. pestis, the
causative agent of plague. Here, the contribution of Ail for Y. pestis survival in the flea vector …

Endotoxin: Structure Source and Effects

A Perrella, N Carannante, N Capoluongo… - … Induced-Shock: a …, 2023 - Springer
Endotoxins are insoluble parts of the bacterial cells able to evoke a typical clinical picture
characterizing bacterial infection. Usually, Gram-negative bacteria are a major part of the gut …