Necrotizing enterocolitis, gut microbes, and sepsis

JW Duess, ME Sampah, CM Lopez, K Tsuboi… - Gut …, 2023 - Taylor & Francis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the
leading cause of death and disability from gastrointestinal disease in this vulnerable …

High-frequency ventilation in preterm infants and neonates

BW Ackermann, D Klotz, R Hentschel, UH Thome… - Pediatric …, 2023 - nature.com
High-frequency ventilation (HFV) has been used as a respiratory support mode for neonates
for over 30 years. HFV is characterized by delivering tidal volumes close to or less than the …

European consensus guidelines on the management of respiratory distress syndrome: 2022 update

DG Sweet, VP Carnielli, G Greisen, M Hallman… - Neonatology, 2023 - karger.com
Respiratory distress syndrome (RDS) care pathways evolve slowly as new evidence
emerges. We report the sixth version of “European Guidelines for the Management of RDS” …

Intermittent hypoxemia and bronchopulmonary dysplasia with pulmonary hypertension in preterm infants

SJ Gentle, CP Travers, A Nakhmani, P Indic… - American journal of …, 2023 - atsjournals.org
Rationale: Bedside biomarkers that allow early identification of infants with
bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) are critically …

Cardiorespiratory monitoring data to predict respiratory outcomes in extremely preterm infants

N Ambalavanan, DE Weese-Mayer… - American journal of …, 2023 - atsjournals.org
Rationale: Immature control of breathing is associated with apnea, periodic breathing,
intermittent hypoxemia, and bradycardia in extremely preterm infants. However, it is not clear …

Gut microbiome and retinopathy of prematurity

JY Zhang, MJ Greenwald, SH Rodriguez - The American Journal of …, 2023 - Elsevier
Retinopathy of prematurity (ROP), a leading cause of childhood blindness worldwide, is
strongly associated with gestational age and weight at birth. Yet, many extremely preterm …

Invasive and non-invasive ventilatory strategies for early and evolving bronchopulmonary dysplasia

M Sahni, V Bhandari - Seminars in Perinatology, 2023 - Elsevier
In the age of surfactant and antenatal steroids, neonatal care has improved outcomes of
preterm infants dramatically. Since the early 2000's neonatologists have strived to decrease …

[HTML][HTML] The Practice of Enteral Nutrition: Clinical Evidence for Feeding Protocols

AA Salas, CP Travers - Clinics in perinatology, 2023 - ncbi.nlm.nih.gov
Most of the cumulative nutritional deficits in preterm infants occur in the first 2 weeks after
birth. Limited enteral nutrition during the first 2 weeks is one of the critical barriers to solving …

The need to address sex as a biological variable in neonatal clinical studies

K Lingappan, P Alur, E Eichenwald - The Journal of Pediatrics, 2023 - jpeds.com
Male sex has been identified as a risk factor associated with mortality in preterm neonates. 1-
4 Even though male preterm neonates have shown faster declines in mortality, respiratory …

Identifying novel candidate compounds for therapeutic strategies in retinopathy of prematurity via computational drug-gene association analysis

EF Xie, S Hilkert Rodriguez, B Xie, M D'Souza… - Frontiers in …, 2023 - frontiersin.org
Purpose Retinopathy of prematurity (ROP) is the leading cause of preventable childhood
blindness worldwide. Although interventions such as anti-VEGF and laser have high …