[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Decoding enhancer complexity with machine learning and high-throughput discovery

GD Smith, WH Ching, P Cornejo-Páramo, ES Wong - Genome biology, 2023 - Springer
Enhancers are genomic DNA elements controlling spatiotemporal gene expression. Their
flexible organization and functional redundancies make deciphering their sequence-function …

Next-generation plasmids for transgenesis in zebrafish and beyond

CL Kemmler, HR Moran, BF Murray… - …, 2023 - journals.biologists.com
Transgenesis is an essential technique for any genetic model. Tol2-based transgenesis
paired with Gateway-compatible vector collections has transformed zebrafish transgenesis …

Systematic part transfer by extending a modular toolkit to diverse bacteria

KW Keating, EM Young - ACS Synthetic Biology, 2023 - ACS Publications
It is impractical to develop a new parts collection for every potential host organism. It is well-
established that gene expression parts, like genes, are qualitatively transferable, but there is …

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea

AP Trigila, VC Castagna, L Berasain… - Molecular Biology …, 2023 - academic.oup.com
The genetic bases underlying the evolution of morphological and functional innovations of
the mammalian inner ear are poorly understood. Gene regulatory regions are thought to …

[HTML][HTML] Zebrafish for the Study of Enhancer Activity in Human Traits and Disease

E Morice, C Calhoun, R Lalonde… - Zebrafish Research-An …, 2023 - intechopen.com
Enhancers are genetically encoded elements that are critical for controlling gene
expression. Despite the importance of enhancers in development, normal biological …

Enhancers display constrained sequence flexibility and context-specific modulation of motif function

F Reiter, BP de Almeida, A Stark - Genome Research, 2023 - genome.cshlp.org
The information about when and where each gene is to be expressed is mainly encoded in
the DNA sequence of enhancers, sequence elements that comprise binding sites (motifs) for …

Function of the Avian Respiratory System

JN Maina - Current Perspectives on the Functional Design of the …, 2023 - Springer
The gas exchange function of the avian respiratory system is explained. The following
important structural—and functional aspects are presented: the mechanisms of airflow …

Promoter element engineering towards modulated and consistent gene expression

KV Presnell - 2023 - repositories.lib.utexas.edu
Metabolic engineering requires precise control over expression strength, which can be
effectively accomplished through engineering of the promoter element. In this regard, there …

[PDF][PDF] Domestication of Nonconventional Gram-negative Bacteria as Synthetic Biology Chassis

KW Keating - 2023 - digital.wpi.edu
Bacteria have evolved to thrive in an astonishing range of conditions, to produce chemicals
and materials useful to humans, and to sense and respond to changes in their environment …