Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus …

M Anselmi, M Baiula, S Spampinato… - Journal of Medicinal …, 2023 - ACS Publications
α4β1 integrin is a cell adhesion receptor deeply involved in the migration and accumulation
of leukocytes. Therefore, integrin antagonists that inhibit leukocytes recruitment are currently …

FLUORESCENCE HYBRIDIZATION IMAGING OF NEUROLOGICAL DISEASE MESSENGER RNAs

E Wickstrom - Nucleic Acids in Medicinal Chemistry and …, 2023 - Wiley Online Library
Monoamine oxidases (MAOs) catalyze the oxidative deamination of many biogenic amines
and are integral proteins found in the mitochondrial outer membrane. Changes in MAO‐A …