Medicinal Chemistry Perspectives on Recent Advances in Src Kinase Inhibitors as a Potential Target for the Development of Anticancer Agents: Biological Profile …
The physiological Src proto‐oncogene is a protein tyrosine kinase receptor that served as
the essential signaling pathway in different types of cancer. Src kinase receptor is divided …
the essential signaling pathway in different types of cancer. Src kinase receptor is divided …
Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer
H Zou, J Luo, Y Guo, T Tong, Y Liu, Y Chen… - Cellular and Molecular …, 2023 - Springer
SRC is the first identified oncogene, and its aberrant activation has been implicated as a
driving event in tumor initiation and progression. However, its role in cancer stemness …
driving event in tumor initiation and progression. However, its role in cancer stemness …
Discovery of New Quinoline-Based Diarylamides as Potent B-RAFV600E/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity
The emergence of cancer resistance to targeted therapy represents a significant challenge
in cancer treatment. Therefore, identifying new anticancer candidates, particularly those …
in cancer treatment. Therefore, identifying new anticancer candidates, particularly those …
Agent enhancing antitumor effect using pyrazolo [3, 4-d] pyrimidine compound
H Irie, K Oguchi, Y Fujioka - US Patent 11,696,917, 2023 - Google Patents
To provide a method for treating cancer using a pyrazolo [3, 4-d] pyrimidine compound or a
salt thereof. The present invention provides an antitumor agent comprising a pyrazolo [3, 4 …
salt thereof. The present invention provides an antitumor agent comprising a pyrazolo [3, 4 …