Emerging designs of aggregation-induced emission luminogens for lipid droplets imaging

F Zhang, X Wu, B Liu, T Han, D Yan, D Wang… - Coordination Chemistry …, 2023 - Elsevier
Lipid droplets (LDs) are organelles that have evolved to store intracellular neutral lipids and
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …

Cellular communication through extracellular vesicles and lipid droplets

I Amarasinghe, W Phillips, AF Hill… - Journal of …, 2023 - Wiley Online Library
Cellular communication is essential for effective coordination of biological processes. One
major form of intercellular communication occurs via the release of extracellular vesicles …

Epsin nanotherapy regulates cholesterol transport to fortify atheroma regression

K Cui, X Gao, B Wang, H Wu, K Arulsamy… - Circulation …, 2023 - Am Heart Assoc
Background: Excess cholesterol accumulation in lesional macrophages elicits complex
responses in atherosclerosis. Epsins, a family of endocytic adaptors, fuel the progression of …

Myopathologic trajectory in Duchenne muscular dystrophy (DMD) reveals lack of regeneration due to senescence in satellite cells

N Cardone, V Taglietti, S Baratto, K Kefi… - Acta Neuropathologica …, 2023 - Springer
Duchenne muscular dystrophy (DMD) is a devastating X-linked muscular disease, caused
by mutations in the DMD gene encoding Dystrophin and affecting 1: 5000 boys worldwide …

A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy

N Southwell, G Primiano, V Nadkarni… - EMBO Molecular …, 2023 - embopress.org
Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from
impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy …

An optimized method for Oil Red O staining with the salicylic acid ethanol solution

J Du, L Zhao, Q Kang, Y He, Y Bi - Adipocyte, 2023 - Taylor & Francis
ABSTRACT Oil Red O (ORO) staining is a commonly used experimental technique to detect
lipid content in cells or tissues. Freshly prepared ORO in 60% isopropanol is the most widely …

Lipidomic analysis of liver lipid droplets after chronic alcohol consumption with and without betaine supplementation

MK Arumugam, SK Perumal, K Rasineni… - Biology, 2023 - mdpi.com
Simple Summary Alcohol-associated liver disease is a major healthcare problem worldwide
and is the third leading cause of preventable deaths in the US. Hepatic steatosis is the …

Detection of gamma radiation processed onion during storage using propidium iodide based fluorescence microscopy

T Sharma, BB Mishra, PS Variyar - Food Chemistry, 2023 - Elsevier
The determination of absorbed dose in gamma radiation processed onion (treated with 20–
100 Gy for sprout inhibition) during storage is an important regulatory requirement to control …

Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment (Video)| JoVE

K Garcia, A Alves, TM Ribeiro-Rodrigues… - JoVE (Journal of …, 2023 - jove.com
Lipid droplets (LDs) are specialized organelles that mediate lipid storage and play a very
important role in suppressing lipotoxicity and preventing dysfunction caused by free fatty …

Evaluation of Lipid Droplet Size and Fusion in Bovine Hepatic Cells

J Yang, F Kang, A Wei, W Lu, X Zhang… - JoVE (Journal of Visualized …, 2023 - jove.com
Lipid droplets (LDs) are organelles that play an important role in lipid metabolism and
neutral lipid storage in cells. They are associated with a variety of metabolic diseases, such …