Progress in thyroid cancer genomics: a 40-year journey
JA Fagin, YE Nikiforov - Thyroid, 2023 - liebertpub.com
Background: Very little was known about the molecular pathogenesis of thyroid cancer until
the late 1980s. As part of the Centennial celebration of the American Thyroid Association …
the late 1980s. As part of the Centennial celebration of the American Thyroid Association …
Mechanistic insights of thyroid cancer progression
LJ Leandro-García, I Landa - Endocrinology, 2023 - academic.oup.com
Differentiated thyroid cancers (DTCs) are primarily initiated by mutations that activate the
MAPK signaling cascade, typically at BRAF or RAS oncoproteins. DTCs can evolve to more …
MAPK signaling cascade, typically at BRAF or RAS oncoproteins. DTCs can evolve to more …
Recapitulating thyroid cancer histotypes through engineering embryonic stem cells
Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …
Omics sciences and precision medicine in thyroid cancer
K Dhuli, MC Medori, K Donato, PE Maltese… - La Clinica …, 2023 - ricerca.unich.it
Background: Thyroid cancer, a heterogeneous disease originating from the thyroid gland,
stands as the predominant endocrine malignan-cy worldwide. Despite advances in …
stands as the predominant endocrine malignan-cy worldwide. Despite advances in …
Targeting mutant-p53 for cancer treatment: Are we there yet?
DV Lim, WH Woo, JX Lim, XY Loh, HT Soh… - Current Molecular …, 2023 - europepmc.org
Mutations in the TP53 gene are the most common among genetic alterations in human
cancers, resulting in the formation of mutant p53 protein (mutp53). Mutp53 promotes …
cancers, resulting in the formation of mutant p53 protein (mutp53). Mutp53 promotes …
Thyroid Oncocytic (Hürthle Cell) Nodules With Longitudinal Nuclear Grooves: Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 15 Cases
D Suster, AC Mackinnon… - Archives of Pathology & …, 2023 - meridian.allenpress.com
Context.—Thyroid nodules with longitudinal nuclear grooves have been widely regarded as
synonymous with papillary thyroid carcinoma (PTC). Objective.—To study a series of cases …
synonymous with papillary thyroid carcinoma (PTC). Objective.—To study a series of cases …
Molecular Pathology of Endocrine Tumors
LA Erickson - Molecular Surgical Pathology, 2023 - Springer
The understanding of the molecular pathology of endocrine tumors has advanced greatly in
recent years. Increasing utilization of technologies, such as fluorescence in situ …
recent years. Increasing utilization of technologies, such as fluorescence in situ …
Does the likelihood of malignancy in thyroid nodules with RAS mutations increase in direct proportion with the allele frequency percentage?
TJ Hudson, MP Pusztaszeri, MP Hier… - … -Head & Neck …, 2023 - journals.sagepub.com
Background Genomic testing has enhanced pre-surgical decision making for cytologically
indeterminate thyroid nodules, but there remains uncertainty regarding RAS mutations. The …
indeterminate thyroid nodules, but there remains uncertainty regarding RAS mutations. The …
Investigating Induction of DNA Damage and Angiogenic Processes as Therapeutic Targets in the Treatment of Anaplastic Thyroid Cancer
RP Mackay - 2023 - search.proquest.com
Anaplastic thyroid cancer (ATC) is the most lethal form of thyroid cancer with a median
survival between 3 to 5 months and accounts for a disproportionate number of thyroid …
survival between 3 to 5 months and accounts for a disproportionate number of thyroid …
[PDF][PDF] Trasformazione di cellule staminali tiroidee in cellule staminali tumorali.
DM BONANNO, SSAG SCONZO - 2023 - core.ac.uk
L'unità funzionale della tiroide è il follicolo, una struttura delimitata da epitelio cubico
semplice che presenta una cavità centrale in cui si raccoglie la colloide. Il follicolo è …
semplice che presenta una cavità centrale in cui si raccoglie la colloide. Il follicolo è …