Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus

JJ Hu, Y Liu, H Yao, B Cao, H Liao, R Yang… - Nature …, 2023 - nature.com
The emergence of consciousness from anesthesia, once assumed to be a passive process,
is now considered as an active and controllable process. In the present study, we show in …

Prognostication in Prolonged and Chronic Disorders of Consciousness

JM Carlson, DJ Lin - Seminars in Neurology, 2023 - thieme-connect.com
Patients with prolonged disorders of consciousness (DOCs) longer than 28 days may
continue to make significant gains and achieve functional recovery. Occasionally, this …

Deep brain stimulation improves electroencephalogram functional connectivity of patients with minimally conscious state

Y Dang, Y Wang, X Xia, Y Yang, Y Bai… - CNS neuroscience & …, 2023 - Wiley Online Library
Aim Deep brain stimulation (DBS) is a potential neuromodulatory therapy that enhances
recovery from disorders of consciousness, especially minimally conscious state (MCS). This …

[HTML][HTML] Transcutaneous vagal nerve stimulation to treat disorders of consciousness: protocol for a double-blind randomized controlled trial

MM Vitello, MM Briand, D Ledoux, J Annen… - International Journal of …, 2023 - Elsevier
Background Patients with disorders of consciousness (DoC) are a challenging population
prone to misdiagnosis with limited effective treatment options. Among neuromodulation …

Mesocircuit mechanisms in the diagnosis and treatment of disorders of consciousness

ND Schiff - La Presse Médicale, 2023 - Elsevier
The 'mesocircuit hypothesis' proposes mechanisms underlying the recovery of
consciousness following severe brain injuries. The model builds up from a single premise …

Reorganized hubs of brain functional networks after acute mild traumatic brain injury

L Bai, B Yin, S Lei, T Li, S Wang, Y Pan… - Journal of …, 2023 - liebertpub.com
Mild traumatic brain injury (mTBI)-associated damage to hub regions can lead to disrupted
modular structures of functional brain networks and may result in widespread cognitive and …

Diagnostic and Therapeutic Approaches in Neurorehabilitation after Traumatic Brain Injury and Disorders of Consciousness

J Lippert, AG Guggisberg - Clinical and Translational Neuroscience, 2023 - mdpi.com
Severe traumatic brain injury (TBI) may cause disorders of consciousness (DoC) in the form
of coma, unresponsive wakefulness syndrome (UWS), or minimally conscious state (MCS) …

The effect of neural pre-stimulus oscillations on post-stimulus somatosensory event-related potentials in disorders of consciousness

L Lindenbaum, I Steppacher, A Mehlmann… - Frontiers in …, 2023 - frontiersin.org
Brain activity of people in a disorder of consciousness (DoC) is diffuse and different from
healthy people. In order to get a better understanding of their cognitive processes and …

Brain Recovery in Childhood: The Interaction Between Developmental Plasticity and Regenerative Mechanisms

F Costanzo, E Fucà, D Menghini, S Vicari - … and Psychological Aspects of …, 2023 - Springer
Stroke is one of the ten leading causes of death in children and adolescents ages 1–18.
Pediatric stroke has some specific characteristics that make it very different from the stroke …

Investigation of Clinical and Neuroimaging Outcomes of Pediatric Non-Fatal Drowning

MS Razaqyar - 2023 - search.proquest.com
Drowning is the leading cause of death for children 1-4 years of age. Pediatric non-fatal
drowning is prevalent in this age group: for every child who dies from drowning, another …