Pathogenesis and treatment of Sjogren's syndrome: review and update
Q Zhan, J Zhang, Y Lin, W Chen, X Fan… - Frontiers in …, 2023 - frontiersin.org
Sjogren's syndrome (SS) is a chronic autoimmune disease accompanied by multiple
lesions. The main manifestations include dryness of the mouth and eyes, along with …
lesions. The main manifestations include dryness of the mouth and eyes, along with …
Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies
GE Thorlacius, A Björk… - Nature Reviews …, 2023 - nature.com
In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …
Biological therapy in systemic lupus erythematosus, antiphospholipid syndrome, and Sjögren's syndrome: evidence-and practice-based guidance
A Marinho, J Delgado Alves, J Fortuna, R Faria… - Frontiers in …, 2023 - frontiersin.org
Systemic lupus erythematosus (SLE), antiphospholipid syndrome (APS), and Sjögren's
syndrome (SS) are heterogeneous autoimmune diseases. Severe manifestations and …
syndrome (SS) are heterogeneous autoimmune diseases. Severe manifestations and …
The role of regulatory T Cells in the onset and progression of primary Sjögren's syndrome
VG Blinova, VI Vasilyev, EB Rodionova, DD Zhdanov - Cells, 2023 - mdpi.com
Regulatory T cells (Tregs) play a key role in maintaining immune balance and regulating the
loss of self-tolerance mechanisms in various autoimmune diseases, including primary …
loss of self-tolerance mechanisms in various autoimmune diseases, including primary …
Outline of Salivary Gland Pathogenesis of Sjögren's Syndrome and Current Therapeutic Approaches
Y Yura, M Hamada - International Journal of Molecular Sciences, 2023 - mdpi.com
Sjögren's syndrome (SS) is an autoimmune disease characterized by the involvement of
exocrine glands such as the salivary and lacrimal glands. The minor salivary glands, from …
exocrine glands such as the salivary and lacrimal glands. The minor salivary glands, from …
The spectrum of extraglandular manifestations in primary sjögren's syndrome
Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …
Role of JAK-STAT signaling pathway in pathogenesis and treatment of primary Sjögren's syndrome
M Li, M Li, L Qiao, C Wu, D Xu, Y Zhao… - Chinese Medical …, 2023 - mednexus.org
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with high prevalence
and possible poor prognosis. Though the pathogenesis of pSS has not been fully …
and possible poor prognosis. Though the pathogenesis of pSS has not been fully …
Treatment with a Lactococcus lactis that chromosomally express E. coli cfaI mitigates salivary flow loss in a Sjögren's syndrome-like disease
A Akgul, CF Freguia, M Maddaloni, C Hoffman… - Scientific Reports, 2023 - nature.com
Sjögren's Syndrome (SjS) results in loss of salivary and lacrimal gland excretion due to an
autoimmune attack on these secretory glands. Conventional SjS treatments address the …
autoimmune attack on these secretory glands. Conventional SjS treatments address the …
Emerging treatment for Sjögren's disease: A review of recent phase II and III trials
RI Fox, CM Fox, SS McCoy - Expert Opinion on Emerging Drugs, 2023 - Taylor & Francis
Introduction Sjögren's Disease, SjD, is a systemic autoimmune disorder characterized by
reduced function of the salivary and lacrimal glands. Patients suffer from dryness, fatigue …
reduced function of the salivary and lacrimal glands. Patients suffer from dryness, fatigue …
French national diagnostic and care protocol for Sjögren's disease
V Devauchelle-Pensec, X Mariette… - La Revue de Médecine …, 2023 - Elsevier
Sjögren's disease (SD), also known as Sjögren's syndrome (SS) or Gougerot-Sjögren's
syndrome in France, is a rare systemic autoimmune disease in its primary form and is …
syndrome in France, is a rare systemic autoimmune disease in its primary form and is …