[HTML][HTML] Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

J Wei, M Li, C Xue, S Chen, L Zheng, H Deng… - Journal of Experimental …, 2023 - Springer
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …

[HTML][HTML] A Circular RNAs: Emerging roles and new insights in human cancers

Z He, Q Zhu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

[HTML][HTML] circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF-β signalling pathway-mediated activation of MMPs in pancreatic cancer

Z Zhao, W Yang, R Kong, Y Zhang, L Li, Z Song… - Molecular Cancer, 2023 - Springer
Background Among digestive tract tumours, pancreatic ductal adenocarcinoma (PDAC)
shows the highest mortality trend. Moreover, although PDAC metastasis remains a leading …

Hypoxia-induced circADAMTS6 in a TDP43-dependent manner accelerates glioblastoma progression via ANXA2/NF-κB pathway

S Zhao, B Li, R Zhao, Z Pan, S Zhang, W Qiu, Q Guo… - Oncogene, 2023 - nature.com
Circular RNAs (circRNAs) play important roles in the malignant progression of tumours.
Herein, we identified an unreported circRNA (hsa-circ-0072688, also named circADAMTS6) …

[HTML][HTML] Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm

M Roshani, D Molavizadeh, S Sadeghi, A Jafari… - Biomedicine & …, 2023 - Elsevier
Gastrointestinal (GI) carcinomas are a group of cancers affecting the GI tract and digestive
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …

CircRNA circSTIL inhibits ferroptosis in colorectal cancer via miR‐431/SLC7A11 axis

Q Li, K Li, Q Guo, T Yang - Environmental Toxicology, 2023 - Wiley Online Library
Ferroptosis is an emerging programmed cell death and plays essential roles in
tumorigenesis, including colorectal cancer (CRC). The present study intended to disclose …

Downregulated circPOKE promotes breast cancer metastasis through activation of the USP10-Snail axis

Y Luo, Q Zhu, S Xiang, Q Wang, J Li, X Chen, W Yan… - Oncogene, 2023 - nature.com
Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of
cancer-related death among females. Metastasis accounts for the majority of BC related …

Systematic characterization and biological functions of non‐coding RNAs in glioblastoma

L Dai, W Liang, Z Shi, X Li, S Zhou, W Hu… - Cell …, 2023 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most malignant and aggressive type of glioma. Non‐
coding RNAs (ncRNAs) are RNAs that do not encode proteins but widely exist in eukaryotic …

[HTML][HTML] EIF4A3-induced exosomal circLRRC8A alleviates granulosa cells senescence via the miR-125a-3p/NFE2L1 axis

J Xing, M Zhang, S Zhao, M Lu, L Lin, L Chen… - Stem Cell Reviews and …, 2023 - Springer
Premature ovarian failure (POF) is an important cause of female infertility and seriously
impacts the physical and psychological health of patients. Mesenchymal stromal cells …

Newly discovered mechanisms that mediate tumorigenesis and tumour progression: circRNA‐encoded proteins

C Wu, S Wang, T Cao, T Huang, L Xu… - Journal of Cellular …, 2023 - Wiley Online Library
Proteins produced by cap‐independent translation mediated by an internal ribosome entry
site (IRES) in circular RNAs (circRNAs) play important roles in tumour progression. To date …