The interplay between integrins and immune cells as a regulator in cancer immunology

Q Zhang, S Zhang, J Chen, Z Xie - International Journal of Molecular …, 2023 - mdpi.com
Integrins are a group of heterodimers consisting of α and β subunits that mediate a variety of
physiological activities of immune cells, including cell migration, adhesion, proliferation …

A systematic computational analysis of Mycobacterium tuberculosis H37Rv and human CD34+ genomic expression reveals crucial molecular entities involved in …

P Koyyada, S Mishra - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
The co-evolution of Mycobacterium tuberculosis H37Rv along with its host systems enables
the pathogenic bacterium to emerge as a multi-drug resistant form. This creates challenges …

MERTK Coordinates Efferocytosis by Regulating Integrin Localization and Activation

BH Dickson, T Tassnim, AL Lam, A Vreize, EN Blythe… - bioRxiv, 2023 - biorxiv.org
Efferocytosis–the phagocytic removal of apoptotic cells–is a central component of tissue
homeostasis, and in many tissues is mediated by the efferocytic receptor MERTK expressed …

β2-integrins in Immunity: New Roles for Old Players

LM Uotila, H Harjunpää, SC Fagerholm - … : Key Effectors of Cell-Matrix and …, 2023 - Springer
Abstract β2-integrins are adhesion-and mechanoreceptors expressed exclusively on
leukocytes. They mediate diverse functions in immunity and are of fundamental importance …