In preeclampsia, the shallow invasion of cytotrophoblast cells to uterine spiral arteries,
leading to a reduction in placental blood flow, is associated with an imbalance of …

Background An antiangiogenic state has emerged as a mechanism of disease in
preeclampsia. Angiogenic biomarkers are used in the risk assessment of this syndrome …

Background Fetal growth restriction (FGR) is associated with a suboptimal intrauterine
environment, which may adversely impact fetal neurodevelopment. However, analysing …

Background In pregnancy, women are encouraged to cease smoking and limit caffeine
intake. We employed objective definitions of smoking and caffeine exposure to assess their …

Background: Preeclampsia and fetal growth restriction (FGR) are both associated with an
increased ratio of sFLT1 (soluble fms-like tyrosine kinase-1) to PlGF (placenta growth factor) …

Preeclampsia (PE) is a heterogeneous disease for which the current clinical classification
system is based on the presence or absence of specific clinical features. PE-associated …

Background Spontaneous preterm birth is the endpoint of multiple different
pathophysiological pathways. Fetal growth restriction, assessed by serial ultrasonic fetal …

Autism is more prevalent in males and males on average score higher on measures of
autistic traits. Placental function is affected significantly by the sex of the fetus. It is unclear if …

Introduction: The pathophysiology of preeclampsia is represented by placental ischemia and
the release of angiogenic factors. Recent research suggests that using the value of the sFtl …

Objectives An abnormal angiogenic profile is present in about one-half of women with
preeclampsia at term. Few studies examined the roles of angiogenic biomarkers in …