[HTML][HTML] Meiotic chromosome structure, the synaptonemal complex, and infertility
In meiosis, homologous chromosome synapsis is mediated by a supramolecular protein
structure, the synaptonemal complex (SC), that assembles between homologous …
structure, the synaptonemal complex (SC), that assembles between homologous …
Testis‐specific serine kinase 3 is required for sperm morphogenesis and male fertility
Background The importance of phosphorylation in sperm during spermatogenesis has not
been pursued extensively. Testis‐specific serine kinase 3 (Tssk3) is a conserved gene, but …
been pursued extensively. Testis‐specific serine kinase 3 (Tssk3) is a conserved gene, but …
The AnnotSV webserver in 2023: updated visualization and ranking
V Geoffroy, JB Lamouche, T Guignard… - Nucleic Acids …, 2023 - academic.oup.com
Much of the human genetics variant repertoire is composed of single nucleotide variants
(SNV) and small insertion/deletions (indel) but structural variants (SV) remain a major part of …
(SNV) and small insertion/deletions (indel) but structural variants (SV) remain a major part of …
[HTML][HTML] Large-scale analysis of de novo mutations identifies risk genes for female infertility characterized by oocyte and early embryo defects
Background Oocyte maturation arrest and early embryonic arrest are important reproductive
phenotypes resulting in female infertility and cause the recurrent failure of assisted …
phenotypes resulting in female infertility and cause the recurrent failure of assisted …
[HTML][HTML] DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia
AK Dicke, A Pilatz, MJ Wyrwoll, M Punab… - Communications …, 2023 - nature.com
Non-obstructive azoospermia, the absence of sperm in the ejaculate due to disturbed
spermatogenesis, represents the most severe form of male infertility. De novo microdeletions …
spermatogenesis, represents the most severe form of male infertility. De novo microdeletions …
The '-ics' of male reproduction: genomics, epigenetics, proteomics, metabolomics, and microbiomics
C Kang, R Bertolla, R Pagani - Current opinion in urology, 2023 - journals.lww.com
Infertility is a common problem for couples with approximately half of cases attributable to
male factor infertility. Although advances in assisted reproductive technology have permitted …
male factor infertility. Although advances in assisted reproductive technology have permitted …
[HTML][HTML] Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function
D Dacheux, G Martinez, CEB Reix, J Beurois, P Lorès… - Elife, 2023 - elifesciences.org
Male infertility is common and complex, presenting a wide range of heterogeneous
phenotypes. Although about 50% of cases are estimated to have a genetic component, the …
phenotypes. Although about 50% of cases are estimated to have a genetic component, the …
[HTML][HTML] Deciphering the therapeutic role of Kigelia africana fruit in erectile dysfunction through metabolite profiling and molecular modelling
Kigelia africana herbal products are often used traditionally to treat erectile dysfunction and
other sexual complaints, but the underlying mechanism is not yet understood. This study …
other sexual complaints, but the underlying mechanism is not yet understood. This study …
Comparison of genetic profiles of neonates in intensive care units conceived with or without assisted reproductive technology
Z Huang, F Xiao, H Xiao, Y Lu, L Yang… - JAMA Network …, 2023 - jamanetwork.com
Importance A growing number of children are conceived with assisted reproductive
technology (ART). However, there is a lack of studies systematically analyzing the genetic …
technology (ART). However, there is a lack of studies systematically analyzing the genetic …
[HTML][HTML] Comprehensive Transcriptome Analysis in the Testis of the Silkworm, Bombyx mori
K Kakino, H Mon, T Ebihara, M Hino, A Masuda… - Insects, 2023 - mdpi.com
Simple Summary Spermatogenesis, an important process in reproduction, is conserved
across species but has unique aspects in silkworms, such as the maintenance of the …
across species but has unique aspects in silkworms, such as the maintenance of the …