Management strategies for severe Pseudomonas aeruginosa infections

H Do Rego, JF Timsit - Current Opinion in Infectious Diseases, 2023 - journals.lww.com
Carbapenem resistance in difficult-to-treat P. aeruginosa (DTR-PA) strains is primarily
mediated by loss or reduction of the OprD porin, overexpression of the cephalosporinase …

Can the future of ID escape the inertial dogma of its past? The exemplars of shorter is better and oral is the new IV

K Davar, D Clark, RM Centor… - Open Forum …, 2023 - academic.oup.com
Like all fields of medicine, Infectious Diseases is rife with dogma that underpins much
clinical practice. In this study, we discuss 2 specific examples of historical practice that have …

Pseudomonas—Spectrum of Disease Presentations for the Inpatient Dermatologist

Y Kye, G Zhao, CV Nguyen - Current Dermatology Reports, 2023 - Springer
Abstract Purpose of Review Pseudomonas aeruginosa-associated cutaneous dermatoses
are reasons for consultation for the inpatient dermatologist. This review provides an …

Effect of restricting piperacillin/tazobactam prescription on rates of antimicrobial resistance in gram-negative bacteria and antibiotic consumption

J Oh, SY Park, JS Lee, SH Lee - European Journal of Clinical Microbiology …, 2023 - Springer
The increasing resistance of gram-negative bacteria is a serious global public health
concern. One way to prevent increasing antibiotic resistance is by implementing the …

Penicillin-Binding Protein 5/6 Acting as a Decoy Target in Pseudomonas aeruginosa Identified by Whole-Cell Receptor Binding and Quantitative Systems …

S López-Argüello, M Montaner… - Antimicrobial agents …, 2023 - Am Soc Microbiol
The β-lactam antibiotics have been successfully used for decades to combat susceptible
Pseudomonas aeruginosa, which has a notoriously difficult to penetrate outer membrane …

[HTML][HTML] Mutators can drive the evolution of multi-resistance to antibiotics

DR Gifford, E Berríos-Caro, C Joerres, M Suñé… - PLoS …, 2023 - journals.plos.org
Antibiotic combination therapies are an approach used to counter the evolution of
resistance; their purported benefit is they can stop the successive emergence of …

Which trial do we need? How to treat Pseudomonas aeruginosa bacteraemia—proposal for an umbrella randomized controlled trial

M Gilboa, D van Duin, D Yahav - Clinical …, 2023 - clinicalmicrobiologyandinfection …
Pseudomonas aeruginosa bacteraemia is a common and severe condition. The prevalence
of P. aeruginosa bacteraemia varies depending on the population and setting. In hospital …

Molecular identification of Pseudomonas aeruginosa and antibiotic resistance testing

EN Varela-Rodríguez, JL Arvizu-Gómez… - GSC Biological and …, 2023 - gsconlinepress.com
Pseudomonas aeruginosa is a Gram-negative bacillus considered an opportunistic
pathogen, usually associated with nosocomial infections in immunocompromised patients …

Gram-Negative Infection

AM Tatara - The Infectious Diseases Consult Handbook: Common …, 2023 - Springer
Gram-negative bacteria are ubiquitous in our environment, microbiome, and consult lists.
From the humble Escherichia coli to the dreaded Pseudomonas aeruginosa, these …